Results 51 to 60 of about 1,227,077 (266)
The American Journal of the Medical Sciences, 1907 n ...
Gautier, A., Rico Oxley, A. J.
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
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Envelope Factorization with Partial Elimination and Recombination, EF-PER, a New Linear RF Architecture [PDF]
Radioengineering, 2015 In this paper, a new architecture for efficient linear radio frequency transmitters is proposed; it includes envelope-tracking (ET) and envelope-elimination-and-restoration (EER) architectures as special instances.
A. Diet, G. Baudoin, S. Lasaulce
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Journal of Epidemiology and Community Health, 2006 Is exposure to antibodies and fatty acids in mother’s milk associated with development of autism? Autism is a disease of unknown aetiology, but complex pathogenesis that seems to have become more common in recent decades. We suggest that efforts exploring the aetiology of autism should pay special attention to patterns of breast and artificial feeding ...
M, Potts, B, Bellows
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
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A RISC-V Fault-Tolerant Soft-Processor Based on Full/Partial Heterogeneous Dual-Core Protection
IEEE AccessThe low probability of single event upsets (SEU) within particular satellite orbits, makes Commercial-off-the-shelf (COTS) electronic components a viable solution for space system implementation, thanks to the introduction of design-level fault tolerance
Francesco Vigli +5 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Healthy lifestyle and life expectancy with and without major chronic disease – a cohort study
Scientific ReportsHealth behaviors affect life expectancy, but whether disease is present can greatly impact both the individual and society. How health behavior is reflected in the utilization of health care services is yet to be investigated to support the impact of ...
Anne Kirstine Eriksen +5 more
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Immunological MedicineMetabolic syndromes including obesity and diabetes are the most common health issues due to insulin resistance, disturbance in glucose homeostasis, lack of exercise, and improper diet.
Asma Draz +7 more
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