Results 41 to 50 of about 358,559 (266)

The impact of obesity on sleep, pulmonary and chest wall restriction in Osteogenesis Imperfecta: a pilot study

open access: yesOrphanet Journal of Rare Diseases
Introduction Osteogenesis Imperfecta (OI) is characterised by brittle bones, severe skeletal deformities, low sleep quality, and restricted breathing. We aimed to distinguish how disease and obesity affect these results.
Ramona De Amicis   +5 more
doaj   +1 more source

Evaluation of food consumption, energy availability and adherence to the Mediterranean dietary pattern in a group of non-professional athletes

open access: yesFrontiers in Nutrition
Background and aimAdequate nutritional intake is fundamental for optimizing athletic performance and maintaining health. The aim of the present study was to investigate the dietary habits of a group of non-professional athletes, assessing their capacity ...
Ellis Bianchi   +14 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The moderating effect of physical activity in the relationship between sleep quality and BMI in adults with overweight and obesity

open access: yesFrontiers in Sports and Active Living
Inadequate sleep quality is a significant risk factor for overweight and obesity, which in turn may predispose individuals to adverse health outcomes.
Letizia Galasso   +17 more
doaj   +1 more source

DeepFood: Food Image Analysis and Dietary Assessment via Deep Model

open access: yesIEEE Access, 2020
Food is essential for human life and has been the concern of many healthcare conventions. Nowadays new dietary assessment and nutrition analysis tools enable more opportunities to help people understand their daily eating habits, exploring nutrition ...
Landu Jiang   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The benefit of diet on paradoxical breathing and sleep in Osteogenesis imperfecta

open access: yesOrphanet Journal of Rare Diseases
We evaluated breathing (i.e.: thoracic contribution to tidal volume in the supine position) and sleep (i.e.: apnea-hypopnea index (AHI)) before and after a 6-month of restricted Mediterranean Diet on 22 volunteers with a confirmed diagnosis of ...
Antonella LoMauro, Ramona De Amicis
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The global diet quality score as an indicator of adequate nutrient intake and dietary quality – a nation-wide representative study

open access: yesNutrition Journal
Background The Global Diet Quality Score (GDQS) was developed to be a simple, timely and cost-effective tool to track, simultaneously, nutritional deficiency and non-communicable disease risks from diet in diverse settings.
Marina M. Norde   +10 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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