Results 101 to 110 of about 246,740 (300)

Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes

Advanced Science, EarlyView.
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin, Karthikeyan Narayanan, Deepak Vashishth   +2 more
wiley   +1 more source

COMPOSIÇÃO CENTESIMAL, COMPOSTOS BIOATIVOS E PARÂMETROS FÍSICO-QUÍMICOS DO JENIPAPO (GENIPA AMERICANA L.) IN NATURA

Demetra, 2015
Introduction: Cerrado is a diversified biome which has many types of fruit species, among which the Genipapo (Genipa americana L.) stands out. Objective: To analyze the centesimal composition, bioactive compounds and physicochemical parameters in in ...
Paula Pacheco, Josiane Gonçalves da Paz, Cassiano Oliveira da Silva, Grazieli Benedetti Pascoal   +3 more
doaj   +1 more source

Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression

Advanced Science, EarlyView.
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang, Tingting Tong, Pengxi Shi, Xiaofan Chen, Chenhao Wang, Qingyuan Weng, Sihan Chen, Linli Que, Qi Chen, Yuehua Li, Qiang Zhu, Jiantao Li   +11 more
wiley   +1 more source

The Benefits and Concerns of Veganism in Women\u27s Health [PDF]

, 2017
There are many health benefits of consuming a vegan diet. It is associated with a decreased incidence of obesity, cardiovascular disease, type two diabetes, and a variety of cancers. Despite its numerous benefits, there are several concerns for consumers
Hester, Elisa R
core   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Feed interventions and skatole deposition [PDF]

, 2012
Skatole produced in the large intestine of the pig and the testicular steroid androstenone are the main substances contributing to boar tainted meat from entire male pigs.
Jensen, Rikke Lassen
core  

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

Carbohydrate consumption and cirrhosis-related mortality: a prospective cohort study

BMC Research Notes
Background Liver cirrhosis is a chronic liver disease that is often associated with poor prognosis. An important part of the treatment of patients with cirrhosis is related to nutrition.
Nastaran Raissi-Dehkordi, Negar Raissi-Dehkordi, Azita Hekmatdoost, Fereshteh Pashayee-khamene, Sara Karimi, Saleheh Ahmadzadeh, Mehdi Saberifiroozi, Behzad Hatami, Hossein Hatami, Zahra Yari   +9 more
doaj   +1 more source

Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD

International Journal of Endocrinology, 2013
Is steatosis related to the spontaneous carbohydrate intake in patients with NAFLD? We performed dietary records for 24 patients with NAFLD, 3 months after their liver biopsy was performed and before the deliverance of a dietary advice. The food quotient,
Concepcion Gonzalez, Victor de Ledinghen, Julien Vergniol, Juliette Foucher, Brigitte Le Bail, Sabrina Carlier, Elisa Maury, Henri Gin, Vincent Rigalleau   +8 more
doaj   +1 more source

The Role of Supplemental Complex Dietary Carbohydrates and Gut Microbiota in Promoting Cardiometabolic and Immunological Health in Obesity: Lessons from Healthy Non-Obese Individuals

Frontiers in Nutrition, 2017
Dietary supplementation with complex carbohydrates is known to alter the composition of gut microbiota, and optimal implementation of the use of these so called “prebiotics” could be of great potential in prevention and possibly treatment of obesity and ...
Petra C. Vinke, Sahar El Aidy, Gertjan van Dijk   +2 more
doaj   +1 more source