Results 291 to 300 of about 1,214,029 (356)

Pharmacomicrobiomics

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Oral medications encounter gut commensal microbes that participate directly and indirectly in drug effects through metabolism, interactions with drug metabolites, or production of substrates that compete with drugs for drug‐metabolizing enzymes, consequently influencing drug pharmacokinetics.
Naomi Gronich   +11 more
wiley   +1 more source

Family's socioeconomic and demographic factors on elements of children's dental and oral health: A scoping review

open access: yesClinical and Experimental Dental Research, EarlyView.
Abstract Background Family plays a significant role in children's dental and oral health (DOH) elements, such as children's DOH knowledge and practice, the development of children's dental fear and anxiety (DFA), children's dental visits, and children's DOH status.
Wisnu Fadila   +5 more
wiley   +1 more source

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

open access: yesBarrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source

Identification of Candidate Blood Biomarkers of Recombinant Human Erythropoietin Administration Using Targeted Polar Metabolomics by HILIC‐MS/MS

open access: yesDrug Testing and Analysis, EarlyView.
Using targeted HILIC‐MS/MS metabolomics, inosine and hypoxanthine were identified as potential biomarkers of EPO administration. Their consistent and sensitive plasma responses highlight their promise for inclusion in the Athlete Biological Passport (ABP), warranting further investigation to enhance anti‐doping detection strategies. ABSTRACT Increasing
Olivier Salamin   +5 more
wiley   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim   +4 more
wiley   +1 more source

Insulin‐Related Disordered Eating Behavior: Clarifying Terminology

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objectives Consistent terminology for disordered eating behaviors relating to insulin manipulation is needed to consolidate and harmonize knowledge across research and practice. The aim of this study was to explore the terminology used to describe insulin‐related disordered eating behaviors in people with type 1 diabetes and suggest ...
Amy Shelford   +2 more
wiley   +1 more source

“This Is Not My Food”: Exploring Experiences Among Patients With a Migration Background in Specialist Eating Disorder Treatment in Sweden

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Existing evidence on eating disorders (EDs) among migrant groups across the Global North is sparse and mixed, possibly reflecting the heterogeneity of these populations. This qualitative study explored experiences among patients with a migration background in Swedish specialist ED treatment, with a focus on barriers to treatment ...
Mattias Strand   +2 more
wiley   +1 more source

Artificial Intelligence in Eating Disorder Treatment: A Qualitative Analysis of Clinical Opportunities, Barriers, and Ethical Considerations From Multi‐Disciplinary Focus Groups

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study explored eating disorder and Artificial Intelligence (AI) professionals' perspectives on how AI might support eating disorder treatment. Successful implementation requires insight into implementation partners' perspectives.
J. Maas   +9 more
wiley   +1 more source

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