Results 151 to 160 of about 2,497,318 (262)

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia   +15 more
wiley   +1 more source

Development of a dichotomous indicator for population-level assessment of dietary diversity in women of reproductive age

open access: yes, 2017
Background: Dietary diversity is a key element of diet quality, but diets of women of reproductive age (WRA; aged 15-49 y) in resource-poor settings are often deficient in a range of micronutrients.
Dop, M. C.   +12 more
core  

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

open access: yesAdvanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu   +10 more
wiley   +1 more source

Urbanization Drives Patterns of Individual Specialization but Not Dietary Diversity Among Coyotes. [PDF]

open access: yesEcol Evol
Kreling SES   +6 more
europepmc   +1 more source

FOOD SECURITY INCIDENCES BASED ON DIETARY ENERGY CONSUMPTION, DIETARY DIVERSITY AND HOUSEHOLD FOOD INSECURITY ACCESS SCALE IN CHAMWINO DISTRICT, TANZANIA

open access: yes, 2016
Dietary energy consumption (DEC), dietary diversity (DD) and household food insecurity access scale ...
† ---Kim A Kayunze, Emiliana A Assenga
core  

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

open access: yesAdvanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu   +6 more
wiley   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

open access: yesAdvanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao   +9 more
wiley   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

open access: yesAdvanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie   +7 more
wiley   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

open access: yesAdvanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai   +12 more
wiley   +1 more source

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