Results 11 to 20 of about 16,442 (242)

Age-Related Mitochondrial DNA Deletion in Rat Liver Depends on Dietary Fat Unsaturation [PDF]

The Journals of Gerontology: Series A, 2006
We fed male Wistar rats lifelong on virgin olive (rich in the monounsaturated oleic acid) or sunflower (rich in the polyunsaturated linoleic acid) oil-based diets. At 6 and 24 months, liver mitochondria were analyzed for a mitochondrial DNA (mtDNA) deletion, reactive oxygen species, antioxidants, and ultrastructural alterations.
José L, Quiles, Julio J, Ochoa, M Carmen, Ramirez-Tortosa, Jesús R, Huertas, José, Mataix   +4 more
openaire   +2 more sources

Healthy grocery delivery in the usual care for adults recovering from an acute coronary event: protocol for a three-arm randomised controlled trial

BMJ Open, 2023
Introduction Coronary heart disease is a major contributor to the global burden of disease. Appropriate nutrition is a cornerstone of the prevention and treatment of coronary heart disease; however, barriers including cost and access to recommended foods
Jim Mann, Sean Coffey, Huan Chan, Robin Turner, Alastair Ross, Ross Wilson, Fiona Hood, Ella Iosua, Andrew N Reynolds, Silke Neumann, Rajesh Katare, Aysu Shahin, Zi-yi Kok   +12 more
doaj   +1 more source

Increased Consumption of Unsaturated Fatty Acids Improves Body Composition in a Hypercholesterolemic Chinese Population

Frontiers in Nutrition, 2022
While an increase in fat intake and the resulting excess calorie intake are implicated in weight gain, different fat types exert variable effects on body composition, with unsaturated fats showing favorable effects on body composition in Western ...
Sumanto Haldar, Shalini Ponnalagu, Farhana Osman, Shia Lyn Tay, Long Hui Wong, Yuan Rong Jiang, Melvin Khee Shing Leow, Melvin Khee Shing Leow, Melvin Khee Shing Leow, Christiani Jeyakumar Henry, Christiani Jeyakumar Henry   +10 more
doaj   +1 more source

Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil. [PDF]

PLoS ONE, 2015
As dietary saturated fatty acids are associated with metabolic and cardiovascular disease, a potentially interesting strategy to reduce disease risk is modification of the quality of fat consumed.
Martine C Morrison, Petra Mulder, P Mark Stavro, Manuel Suárez, Anna Arola-Arnal, Wim van Duyvenvoorde, Teake Kooistra, Peter Y Wielinga, Robert Kleemann   +8 more
doaj   +1 more source

A healthy approach to dietary fats: understanding the science and taking action to reduce consumer confusion

Nutrition Journal, 2017
Consumers are often confused about nutrition research findings and recommendations. As content experts, it is essential that nutrition scientists communicate effectively. A case-study of the history of dietary fat science and recommendations is presented,
Ann G. Liu, Nikki A. Ford, Frank B. Hu, Kathleen M. Zelman, Dariush Mozaffarian, Penny M. Kris-Etherton   +5 more
doaj   +1 more source

Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics. [PDF]

PLoS ONE, 2008
BACKGROUND: The effect of dietary fats on human health and disease are likely mediated by changes in gene expression. Several transcription factors have been shown to respond to fatty acids, including SREBP-1c, NF-kappaB, RXRs, LXRs, FXR, HNF4alpha, and ...
Linda M Sanderson, Philip J de Groot, Guido J E J Hooiveld, Arjen Koppen, Eric Kalkhoven, Michael Müller, Sander Kersten   +6 more
doaj   +1 more source

Review of the evidence for the potential impact and feasibility of substituting saturated fat in the New Zealand diet

Australian and New Zealand Journal of Public Health, 2013
Objective: To estimate the potential impact on cardiovascular health of modifying dietary intake of saturated fat across the New Zealand population, and whether this would be appropriate and feasible.
Rachel H. Foster, Nick Wilson
doaj   +1 more source

Endocannabinoid signaling in the gut mediates preference for dietary unsaturated fats

The FASEB Journal, 2013
Dietary fat exerts a potent stimulatory effect on feeding. This effect is mediated, at least in part, by a cephalic mechanism that involves recruitment of the vagus nerve and subsequent activation of endocannabinoid signaling in the gut.
DiPatrizio, Nicholas V, Joslin, Alexandra, Jung, Kwang‐Mook, Piomelli, Daniele   +3 more
openaire   +5 more sources

Unsaturated or saturated dietary fat-mediated steatosis impairs hepatic regeneration following partial hepatectomy in mice

PLOS ONE, 2023
BackgroundPartial hepatectomy is a preferred treatment option for many patients with hepatocellular carcinoma however, pre-existing pathological abnormalities originating from hepatic steatosis can alter the decision to perform surgery or postoperative outcomes as a consequence of the impact steatosis has on liver regeneration.AimThe aim of this study ...
S. M. Touhidul Islam, Arun P. Palanisamy, Gabriel R. Chedister, Michael G. Schmidt, David N. B. Lewin, Kenneth D. Chavin   +5 more
openaire   +2 more sources

Fatty acids from diet and microbiota regulate energy metabolism [version 1; referees: 2 approved]

F1000Research, 2015
A high-fat diet and elevated levels of free fatty acids are known risk factors for metabolic syndrome, insulin resistance, and visceral obesity. Although these disease associations are well established, it is unclear how different dietary fats change the
Joe Alcock, Henry C. Lin
doaj   +1 more source