Results 111 to 120 of about 1,436,028 (329)

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

Advanced Science, EarlyView.
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun, Yong‐Bing Wang, Jing Huang, Run‐Wei Deng, Hui‐Yu He, Lei Gao, Xuan Gao, You‐Li Fan, Yan Cong, Yao‐Lei Guo, Yi‐Qiang Chen, Gui‐Jia Wang, Shao‐Hong Fang, Xia Gu, Bo Yu, Bing‐Xiang Wu   +15 more
wiley   +1 more source

Familial resemblance in dietary intake among singletons, twins, and spouses: a meta-analysis of family-based observations

BMC Public Health
Background Familial dietary intake can be influenced by both genetic and environmental factors; the current study aimed to examine the role of these two factors on dietary intake by investigating the resemblance in energy, nutrient, and food group intake
Farshad Teymoori, Mahdi Akbarzadeh, Mostafa Norouzzadeh, Mitra Kazemi Jahromi, Hossein Farhadnejad, Niloufar Saber, Hamid Ahmadirad, Mina Jahangiri, Danial Habibi, Parisa Riahi, Ebrahim Mokhtari, Maryam Zarkesh, Maryam S. Daneshpour, Parvin Mirmiran, Mohammadreza Vafa   +14 more
doaj   +1 more source

Dietary fats and serum lipids in relation to the risk of ovarian cancer: a meta-analysis of observational studies. [PDF]

Front Nutr, 2023
Zhang X, Ding HM, Deng LF, Chen GC, Li J, He ZY, Fu L, Li JF, Jiang F, Zhang ZL, Li BY.   +10 more
europepmc   +1 more source

The Effect of Dietary Fat on the Development of Vitamin B6 Deficiency in the Rat [PDF]

, 1959
Mary Ann Williams, Nina L. Cohen, Bernard Hata   +2 more
openalex   +1 more source

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

Advanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge, Shuying Wang, Zhaokai Li, Jing Yu, Binbin Liu, Ruiying Wang, Shichen Bu, Nawsher wan, Yan Wang, Cuilian Dai, Yijun Lin   +10 more
wiley   +1 more source

Dietary Fats and Cardio-Metabolic Outcomes in a Cohort of Italian Adults. [PDF]

Nutrients, 2022
Currenti W, Godos J, Alanazi AM, Grosso G, Cincione RI, La Vignera S, Buscemi S, Galvano F.   +7 more
europepmc   +1 more source

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

Advanced Science, EarlyView.
Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li, Xinrui Li, Yuhui Du, Sijie Chen, Xiaoniu He, Zhangrong Xie, Zhiqing Zhou, Huijie Zhao, Xiaofei Zeng, Guoan Chen   +9 more
wiley   +1 more source

Nutritional quality of dietary patterns of children: are there differences inside and outside school?

Jornal de Pediatria
: Objectives: To describe the dietary patterns of children inside and outside school and investigate their associations with sociodemographic factors and nutritional status.
Diva Aliete dos Santos Vieira, Michelle Alessandra Castro, Mauro Fisberg, Regina Mara Fisberg   +3 more
doaj   +1 more source

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang, Shengtao Cheng, Huiying Gu, Shan Zhong, Dapeng Zhang, Xin He, Weixian Chen, Haijun Deng, Jihua Ren, Peng Chen, Ming Tan, Hui Zhang, Fan Li, Zhenzhen Zhang, Yuan Hu, Juan Chen   +15 more
wiley   +1 more source

Sterol Balance in Man as Plasma Cholesterol Concentrations Are Altered by Exchanges of Dietary Fats* [PDF]

, 1965
Norton Spritz, E. H. Ahrens, Scott M. Grundy   +2 more
openalex   +1 more source