Results 131 to 140 of about 1,436,028 (329)

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

open access: yesAdvanced Science, EarlyView.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang   +6 more
wiley   +1 more source

Changes in the gene expression profile of the mammary gland lipogenic enzymes in Saanen goats in response to dietary fats. [PDF]

open access: yesVet Med Sci, 2023
Javaheri Barfourooshi H   +5 more
europepmc   +1 more source

Association of Specific Dietary Fats With Total and Cause-Specific Mortality.

open access: yesJAMA Internal Medicine, 2016
Dong D. Wang   +7 more
semanticscholar   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

open access: yesAdvanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu   +18 more
wiley   +1 more source

Pharmacological potential of endocannabinoid and endocannabinoid-like compounds in protecting intestinal structure and metabolism under high-fat conditions

open access: yesFrontiers in Pharmacology
The intestine plays a crucial role in nutrient absorption, digestion, and regulation of metabolic processes. Intestinal structure and functions are influenced by several factors, with dietary composition being one of the most significant.
Francesco Vari   +9 more
doaj   +1 more source

The Role of Dietary Fats in the Development and Prevention of Necrotizing Enterocolitis. [PDF]

open access: yesNutrients, 2021
Alshaikh BN   +4 more
europepmc   +1 more source

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

open access: yesAdvanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo   +10 more
wiley   +1 more source

Effects of milk fat, unhydrogenated and partially hydrogenated vegetable oils on fat metabolism of growing pigs: I. Growth, feed utilization and carcass quality in pigs fed different fats and oils

open access: yesAgricultural and Food Science, 1993
Two trials were conducted to study the effects of different dietary fats on the performance, carcass quality and meat quality of 75 crossbred growing pigs.
Kaija Suomi   +4 more
doaj   +2 more sources

Dietary Fat in the Nutrition of the Growing Chick

open access: hybrid, 1958
N.T. Rand, H.M. Scott, F. A. Kummerow
openalex   +1 more source

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