Results 261 to 270 of about 1,436,028 (329)

Graphitized Biochar Derived from Agricultural Wastes Enhances Methanogenesis via Conductivity‐Driven Direct Interspecies Electron Transfer

Advanced Science, EarlyView.
This work clarifies how feedstocks and their structural features promote methanogenesis, and identifies the key regulatory factors, reducing pollution to the global environment, and also helps to alleviate the energy crisis. This is the first study to systematically link feedstock lignin content, pyrolysis conditions, biochar graphitization, and DIET ...
Caiyun Yang, Zhen Liu, Weiguo Liu, Yuxin Qiu, Shuai Zhang, Xinke Zhang, Mengyi Wang, Heng Wu, Hongyi Lyu, Jinzhi Huang, Jia Liu, Yirong Wang, Siying He, Dongze Gu, Xiaohui Guo, Xuanmin Yang, Teng Xie, Heyu Chen, Yiqing Yao   +18 more
wiley   +1 more source

Hyperspectral Fluorescence Imaging with a New Polarity‐Ultrasensitive Fluorescent Probe

Advanced Science, EarlyView.
Based on the critical role of the π‐spacer in determining wavelength sensitivity to microenvironmental polarity, a new fluorescent probe, Lipi‐PS is rationally developed, which exhibits the highest polarity‐sensitivity so far. Its integration with hyperspectral fluorescence imaging enables multiscale polarity mapping across cells, tissues, and ...
Ri Zhou, Hao Sha, Shengjie Fu, Guannan Liu, Jinbei Wei, Chenguang Wang, Shangguo Hou, Geyu Lu   +7 more
wiley   +1 more source

Deficiency of Leucine‐Rich Repeat Containing G Protein‐Coupled Receptor 4 in Pancreas Reduces β Cell Mass

Advanced Science, EarlyView.
In islet β cells, LGR4 binds with Rspondin to activate the Wnt‐β‐catenin‐Ccnd1 axis, leading to a subsequent increase in cell proliferation. On the other hand, LGR4 also binds with RANKL, thus suppressing the phosphorylation of p44/p42 MAPK and p65 NF‐κB and subsequent cell apoptosis.
Chao Luo, Yifan Feng, Jiajie Min, Yan Zhao, Ziming Zhu, Lijun Sun, Hao Yin, Yue Yin, Weizhen Zhang   +8 more
wiley   +1 more source

Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

Advanced Science, EarlyView.
The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley   +1 more source

Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake

Advanced Science, EarlyView.
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan, Xin‐Ning Li, Zhong‐Liang Peng, Wei Wu, Zeng Wang, Zhao‐Ran Zhu, Jia‐Chang Liu, Yao Wang, Jin‐Long Ren, Zhi‐Yi Zhang, Jia‐Tang Li   +10 more
wiley   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

Advanced Science, EarlyView.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu, Jia Yan, Yuyan Zhang, Xiaozhi Ming, Siqi Chen, Zhichao Zou, Nianjie Feng, Jianbo Xiao   +7 more
wiley   +1 more source

Dietary fats and mortality among patients with type 2 diabetes: analysis in two population based cohort studies.

BMJ, 2019
Jiao J, Liu G, Shin HJ, Hu FB, Rimm EB, Rexrode KM, Manson JE, Zong G, Sun Q.   +8 more
europepmc   +1 more source

Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association

Circulation, 2017
Frank M Sacks, Alice H Lichtenstein, Jason Hy Wu   +2 more
exaly   +2 more sources