Results 161 to 170 of about 2,252,340 (352)

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

The moderating effect of dietary fiber intake on the association between sleep pattern and liver fibrosis in metabolic dysfunction-associated steatotic liver disease: a study from NHANES

BMC Gastroenterology
Background Insufficient nocturnal sleep was associated with a higher risk of fibrosis in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).
Guoqing Jia, Mengzhen Jia, Chuntao Li
doaj   +1 more source

Effects of three extraction methods on the structural and functional properties of insoluble dietary fibers from mycoprotein

, 2023
Xuewen Zhang, Yan Zeng, Juanjuan Liu, Yan Men, Yuanxia Sun   +4 more
openalex   +1 more source

The Association of Dietary Fiber Intake in Three Meals with All-Cause and Disease-Specific Mortality among Adults: The U.S. National Health and Nutrition Examination Survey, 2003–2014 [PDF]

, 2022
Jiayue Qi, Jian Gao, Yuntao Zhang, Wanying Hou, Tianshu Han, Changhao Sun   +5 more
openalex   +1 more source

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

Cell, 2016
A. Koh, F. Vadder, P. Kovatcheva-Datchary, F. Bäckhed   +3 more
semanticscholar   +1 more source

MicroRNA‐Enriched Plant‐Derived Exosomes Alleviate Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota

Advanced Science, EarlyView.
Herbal medicine, with its multicomponent and multitarget potential, is often studied primarily for traditional forms, especially phytochemicals. Currently, ulcerative colitis lacks natural, low‐toxicity therapies, yet emerging research highlights plant‐derived exosomes as a promising option.
Ruipeng Shi, Wen Tan, Haochun Jin, Sio I Chan, Wei Li, Si San Lei, Guozhen Cui, Yitao Wang, Dong‐Hua Yang, Zhangfeng Zhong   +9 more
wiley   +1 more source

Redox Cascade in Chicken Skeletal Muscle: SELENOT Suppression in Selenium Deficiency Triggers Disulfidptosis via mtROS‐NADPH Dysregulation

Advanced Science, EarlyView.
Se deficiency downregulates SELENOT, disrupting mitochondrial function and elevating mtROS to induce glucose metabolic reprogramming, NADPH depletion, cysteine accumulation, and disulfidptosis‐mediated actin cytoskeleton collapse in chicken skeletal muscle.
Huanyi Liu, Hao Wu, Ziyu Zhang, Shiwen Xu, Cong Zhou, Tong Xu   +5 more
wiley   +1 more source

Research Advances in the Role of Cereal Dietary Fiber in Modulating Glucose and lipid Metabolism via the Gut Microbiota-Bile Acid

Liang you shipin ke-ji
Disorders in glucose and lipid metabolism are closely linked to chronic metabolic diseases, including obesity, non-alcoholic fatty liver, hyperlipidemia and diabetes.
DONG Hong-wang, QI Wen-tao, PENG Wen-ting, SONG Ge, FANG Wei   +4 more
doaj   +1 more source

Dietary fiber-based colon-targeted delivery systems for polyphenols

, 2020
Hsi-Yang Tang, Zhongxiang Fang, Ken Ng
openalex   +2 more sources

Dietary Fiber Intake among Normal-Weight and Overweight Female Health Care Workers: An Exploratory Nested Case-Control Study within FINALE-Health [PDF]

, 2017
Jenny Hadrévi, Karen Søgaard, Jeanette Reffstrup Christensen   +2 more
openalex   +1 more source