Results 81 to 90 of about 541,679 (339)

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Factors affecting sorghum protein digestibility [PDF]

, 2003
In the semi-arid tropics worldwide, sorghum (Sorghum bicolor (L.) Moench) is cultivated by farmers on a subsistence level and consumed as food by humans.
Belton, Peter, Duodu, K, Hamaker, BR, Taylor, JRN   +3 more
core   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Fish larval nutrition and feed formulation: knowledge gaps and bottlenecks for advances in larval rearing [PDF]

, 2013
Despite considerable progress in recent years, many questions regarding fish larval nutrition remain largely unanswered, and several research avenues remain open.
Applebaum, Aragão, Aragão, Aragão, Aragão, Arthur, Atalah, Atalah, Baer, Barr, Baskerville-Bridges, Benítez-Santana, Berridge, Bessonart, Betancor, Betancor, Blaxter, Bransden, Buentello, Busch, Caballero, Caballero, Caballero, Cahu, Cahu, Cahu, Carvalho, Carvalho, Carvalho, Cetta, Chen, Chen, Conceição, Conceição, Conceição, Conceição, Conceição, Conceição, Conceição, Conceição, Conceição, Copeman, Curnow, Dantagnan, Darias, Day, Dedi, Deplano, Dhert, Dhert, Dhont, Ebrahimnezhadarabi, Engrola, Engrola, Estévez, Estévez, Faleiro, Fernández, Fernández, Fernández, Field, Finn, Finn, Finn, Fleming, Fontagné, Fontagné, Fontagné, Fraser, Gatesoupe, Geurden, Geurden, Gouillou-Coustans, Hadas, Haga, Hamre, Hamre, Hamre, Hamre, Hamre, Hamre, Hamre, Hamre, Hamre, Hamre, Hamre, Hamre, Hamza, Harada, Harada, Harboe, Hastey, Hawkyard, Helland, Heming, Hernández-Cruz, Holt, Hughes, Izquierdo, Izquierdo, Izquierdo, Izquierdo, Izquierdo, Izquierdo, Izquierdo, Kanazawa, Kanazawa, Kleinow, Kolkovski, Kolkovski, Kolkovski, Kolkovski, Kolkovski, Koven, Koven, Koven, Koven, Koven, Kvåle, Kvåle, Langdon, Langdon, Langdon, Lewis-McCrea, Lie, Lindemann, Liu, Lopez-Alvarado, Lowry, Lubzens, Lubzens, Maeland, Maeland, Mai, Martins, Mazurais, McEvoy, Merchie, Mollan, Monroig, Montero, Morais, Morais, Morais, Morais, Morais, Morais, Morais, Moren, Moren, Moren, Morris, Mourente, Mourente, Naess, Nankervis, Nankervis, Navarro, Nguyen, Nicklason, Nordgreen, Nordgreen, Nordgreen, NRC, Ohkubo, Oikawa, Oliva-Teles, Olsen, Onal, Onal, Osse, Otterlei, Ozkizilcik, Parra, Penglase, Penglase, Perumal, Pinto, Pinto, Quantz, Rainuzzo, Rainuzzo, Ribeiro, Rodríguez, Rodríguez, Rodríguez, Rodríguez, Rojas-García, Romero-Romero, Roo, Rubio, Rønnestad, Rønnestad, Rønnestad, Rønnestad, Rønnestad, Rønnestad, Rønnestad, Rønnestad, Rønnestad, Rønnestad, Rønnestad, Saavedra, Saavedra, Saavedra, Saavedra, Saavedra, Salhi, Salhi, Salhi, Samaee, Sandel, Sargent, Sato, Seiliez, Shields, Sire, Solbakken, Srivastava, Srivastava, Srivastava, Sturman, Sánchez-Vázquez, Tocher, Tocher, Tocher, Tocher, Tonheim, Tonheim, Tonheim, Tulli, Udagawa, van der Meeren, Vetter, Villalta, Villalta, Villeneuve, Villeneuve, Walford, Watanabe, Watanabe, Weirich, Woodward, Yúfera, Yúfera, Yúfera, Yúfera, Yúfera, Yúfera, Yúfera, Zambonino-Infante, Øie   +251 more
core   +3 more sources

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Uncoupling proteins, dietary fat and the metabolic syndrome

Nutrition & Metabolism, 2006
There has been intense interest in defining the functions of UCP2 and UCP3 during the nine years since the cloning of these UCP1 homologues. Current data suggest that both UCP2 and UCP3 proteins share some features with UCP1, such as the ability to ...
Warden Craig H, Fisler Janis S
doaj   +1 more source

Is Meat the New Tobacco? Regulating Food Demand in the Age of Climate Change [PDF]

, 2019
Switching from a meat-heavy to a plant-based diet is one of the highest-impact lifestyle changes for climate mitigation and adaptation. Conventional demand-side energy policy has focused on increasing consumption of efficient machines and fuels ...
Chenyang, Lingxi
core  

Maternal zinc intakes and homeostatic adjustments during pregnancy and lactation. [PDF]

, 2012
Zinc plays critical roles during embryogenesis, fetal growth, and milk secretion, which increase the zinc need for pregnancy and lactation. Increased needs can be met by increasing the dietary zinc intake, along with making homeostatic adjustments in ...
Donangelo, Carmen, King, Janet
core   +2 more sources