Results 81 to 90 of about 2,005,788 (385)

Multiple dietary supplements do not affect metabolic and cardio-vascular health [PDF]

, 2013
Dietary supplements are widely used for health purposes. However, little is known about the metabolic and cardiovascular effects of combinations of popular over-the-counter supplements, each of which has been shown to have anti-oxidant, anti-inflammatory
Fontana, Luigi, Holloszy, John O, Soare, Andreea, Weiss, Edward P   +3 more
core   +3 more sources

Current regulatory guidelines and resources to support research of dietary supplements in the United States

Critical reviews in food science and nutrition, 2018
The U.S. Dietary Supplement Health and Education Act (DSHEA) established the regulatory framework for dietary supplements as foods through the Food and Drug Administration (FDA). DSHEA outlined the legal definition, labeling requirements, and process for
R. Bailey
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Multi-Omics Analysis in Mouse Primary Cortical Neurons Reveals Complex Positive and Negative Biological Interactions Between Constituent Compounds of Centella asiatica

Pharmaceuticals
Background: A water extract of the Ayurvedic plant Centella asiatica (L.) Urban, family Apiaceae (CAW), improves cognitive function in mouse models of aging and Alzheimer’s disease and affects dendritic arborization, mitochondrial activity, and oxidative
Steven R. Chamberlin, Jonathan A. Zweig, Cody J. Neff, Luke Marney, Jaewoo Choi, Liping Yang, Claudia S. Maier, Amala Soumyanath, Shannon McWeeney, Nora E. Gray   +9 more
doaj   +1 more source

Dietary Supplement Labeling: Cognitive Biases, Market Manipulation & Consumer Choice [PDF]

, 2014
There exists increasing concern that the Dietary Supplements Health and Education Act (DSHEA) has proven ineffective. Much of the concern regards the disparity in legislative treatment between dietary supplements, foods, and pharmaceutical drugs. Namely,
McCann, Michael
core   +1 more source

Concurrent use of prescription drugs and herbal medicinal products in older adults: A systematic review [PDF]

, 2017
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction ...
A Cherubini, A Djuv, A Fugh-Berman, A Gonzalez-Stuart, A Robinson, A Tsang, AA Izzo, AA Izzo, AA Mangoni, AM Loya, Barbara Wider, C Batanero-Hernán, CA Parkman, CC Peng, Claire Goodman, Commission of the European Communities, DH Mehta, DM Qato, DM Qato, DW Kaufman, E Vacas Rodilla, EC Davies, EM Williamson, FP Turkmenoglu, G Nyborg, GW Elmer, J Jerez-Roig, J Kavanagh, J Kennedy, J Ly, J Peklar, J Sultana, JE Souza Silva de, JJ Bruno, JM Dergal, JS Marinac, K Radimer, KA Vickers, L Howell, L Shamseer, L Shane-McWhorter, Leala K. Watson, MA Raji, ME Levine, MHRA, Ipsos MORI, MS Lantz, N Lynch, N Samuels, P Gardiner, P Posadzki, PH Canter, R Delgoda, RL Nahin, S Hilmer, S Singh, S Yoon, SJ Blalock, SJ Yoon, SL Yoon, SR Singh, T Agbabiaka, Taofikat B. Agbabiaka, The Joanna Briggs Institute, W Leiss, X-L Zhang, Z Munn   +65 more
core   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Disclosure and adverse effects of complementary and alternative medicine used by hospitalized patients in the North East of England [PDF]

, 2012
Objectives: This study aimed to investigate the prevalence, disclosure and adverse effects of complementary and alternative medicine (CAM) use in hospitalised patients, and to explore the associations between patients’ perceived side-effects and relevant
Baqir, wasim, Bello, Nusirat, McGarry, Kenneth, Winit -Watjana, Win   +3 more
core   +2 more sources

Prohibited Contaminants in Dietary Supplements

Sports health, 2017
Context: With the increasing use of unregulated dietary supplements, athletes are at continued risk from adverse medical events and inadvertent doping.
Neilson M Mathews
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source