Results 71 to 80 of about 2,037,406 (347)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A comprehensive review of the application of probiotics and postbiotics in oral health

Frontiers in Cellular and Infection Microbiology, 2023
Oral diseases are among the most common diseases around the world that people usually suffer from during their lifetime. Tooth decay is a multifactorial disease, and the composition of oral microbiota is a critical factor in its development.
Aziz Homayouni Rad, Hadi Pourjafar, Esmaeel Mirzakhani   +2 more
doaj   +1 more source

Prevalence of nonvitamin, nonmineral supplement usage among undergraduate students at the University of Wisconsin-Stout [PDF]

, 2004
Plan BThe use of dietary supplements in the United States is increasing due to the growing interest in nutrition. Herbs, amino acids, vitamins, and minerals are all categorized together vaguely as dietary supplements.
Swenson-Ralph, Amy
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The effects of dietary intervention on HIV dyslipidaemia : a systematic review and meta-analysis [PDF]

, 2012
Background Efficacy of dietary intervention for treatment and prevention of HIV-related lipid disturbances has not been well established. Methods We conducted a systematic search of electronic databases supplemented with manual searches and ...
Thomas, G. Neil, Yen-Fu Chen, Shahrad Taheri (57360), G. Neil Thomas (159433), Connock, Martin, Taheri, S., Connock Martin, Russell, Tracy, Tracy Russell, Thomas, G Neil, Shahrad Taheri, Clare Stradling, Clare Stradling (159408), Chen Yen-Fu, Connock, M., Thomas G. Neil, Chen, Yen-Fu, Chen, Y-F.‏‎, Martin Connock (159426), G Neil Thomas, Tracy Russell (159420), Russell Tracy, Yen-Fu Chen (159414), Chen, Yen-Fu; id_orcid, Martin Connock, Taheri, Shahrad, Stradling Clare, Taheri Shahrad, Stradling, Clare   +28 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Mode of administration influences plasma levels of active Centella asiatica compounds in 5xFAD mice while markers of neuroinflammation remain unaltered

Frontiers in Neuroscience
IntroductionA water extract of Centella asiatica (L.) Urban [Apiaceae] (CAW) has demonstrated cognitive-enhancing effects in mouse models of Alzheimer’s disease and aging, the magnitude of which is influenced by whether CAW is delivered in the drinking ...
Alex B. Speers, Alex B. Speers, Kirsten M. Wright, Kirsten M. Wright, Mikah S. Brandes, Mikah S. Brandes, Nareg Kedjejian, Nareg Kedjejian, Donald G. Matthews, Maya Caruso, Christopher J. Harris, Seiji Koike, Seiji Koike, Thuan Nguyen, Thuan Nguyen, Joseph F. Quinn, Joseph F. Quinn, Joseph F. Quinn, Amala Soumyanath, Amala Soumyanath, Nora E. Gray, Nora E. Gray   +21 more
doaj   +1 more source

Can dietary intake influence perception of and measured appearance? A systematic review : dietary intake and appearance [PDF]

, 2015
Appearance-based interventions have had some success in reducing smoking and sun exposure. Appearance may also motivate dietary behavior change if it was established that dietary improvement had a positive impact on appearance.
Perrett, David, Collins, Clare, Whitehead, Ross, Collins, Clare E, Hutchesson, Melinda, Ozakinci, Gozde, Perrett, David Ian, Whitehead, Ross David, Pezdirc, Kristine   +8 more
core   +1 more source

Unapproved Pharmaceutical Ingredients Included in Dietary Supplements Associated With US Food and Drug Administration Warnings

JAMA Network Open, 2018
Key Points Question What are the trends across adulterated dietary supplements associated with a warning released by the US Food and Drug Administration from 2007 through 2016?
Jenna N. Tucker, Tessa Fischer, Laurence Upjohn, D. Mazzera, Madhur Kumar   +4 more
semanticscholar   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A method for the determination of the ingredients of several dietary supplements by liquid chromatography [PDF]

, 2011
The category of products known as dietary supplements covers a wide range of products including multivitamins, herbal supplements and energy drinks. High performance liquid chromatography (HPLC) is a common analytical technique for pharmaceuticals.
Taylor, Whitney Leigh, NC DOCKS at The University of North Carolina at Greensboro   +1 more
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