Results 51 to 60 of about 644,631 (247)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Mode of administration influences plasma levels of active Centella asiatica compounds in 5xFAD mice while markers of neuroinflammation remain unaltered

Frontiers in Neuroscience
IntroductionA water extract of Centella asiatica (L.) Urban [Apiaceae] (CAW) has demonstrated cognitive-enhancing effects in mouse models of Alzheimer’s disease and aging, the magnitude of which is influenced by whether CAW is delivered in the drinking ...
Alex B. Speers, Alex B. Speers, Kirsten M. Wright, Kirsten M. Wright, Mikah S. Brandes, Mikah S. Brandes, Nareg Kedjejian, Nareg Kedjejian, Donald G. Matthews, Maya Caruso, Christopher J. Harris, Seiji Koike, Seiji Koike, Thuan Nguyen, Thuan Nguyen, Joseph F. Quinn, Joseph F. Quinn, Joseph F. Quinn, Amala Soumyanath, Amala Soumyanath, Nora E. Gray, Nora E. Gray   +21 more
doaj   +1 more source

A comprehensive review of the application of probiotics and postbiotics in oral health

Frontiers in Cellular and Infection Microbiology, 2023
Oral diseases are among the most common diseases around the world that people usually suffer from during their lifetime. Tooth decay is a multifactorial disease, and the composition of oral microbiota is a critical factor in its development.
Aziz Homayouni Rad, Hadi Pourjafar, Esmaeel Mirzakhani   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Nutritional supplements during breastfeeding [PDF]

, 2011
Women who are breastfeeding have increased requirements for energy and nutrients. Nutritional requirements for lactation have been the subject of several international reports and are included in general nutrient requirements documents, including those ...
Binns, C.W., Scott, J., Lee, M., Zhao, Yun, Oddy, W., Lee, M.K., Zhao, Y., Binns, Colin   +7 more
core  

Seven distinct dietary patterns identified among pregnant Finnish women--associations with nutrient intake and sociodemographic factors. [PDF]

, 2007
OBJECTIVES: To identify and describe dietary patterns in a cohort of pregnant women and investigate whether the dietary patterns are associated with dietary intake and sociodemographic factors.
Veijola, Riitta, Suvi M Virtanen, Kenward, Michael G, Mikko Virtanen, Männistö, Satu, Marja-Leena Ovaskainen, Riitta Veijola, Michael G Kenward, Tuula Arkkola, Virtanen, Mikko, Mikael Knip, Knip, Mikael, Arkkola, Tuula, Uusitalo, Ulla, Ulla Uusitalo, Satu Männistö, Kronberg-Kippilä, Carina, Ovaskainen, Marja-Leena, Virtanen, Suvi M, Carina Kronberg-Kippilä   +19 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genotypes pattern of Hepatitis C virus infection in Kermanshah city [PDF]

Journal of Microbiology and Infectious Diseases, 2014
One of the most common causes of chronic liver disease is Hepatitis C all over the world. Furthermore, WHO estimated that the prevalence of HCV isalmost 2-3%,1,2 nonetheless, many studies reported the considerable differences on geographical point of ...
Kioumars Pourrostami, Manoochehr Karami , Enayatollah Kalantar , Feizollah Mansouri   +3 more
doaj   +1 more source

A method for the determination of the ingredients of several dietary supplements by liquid chromatography [PDF]

, 2011
The category of products known as dietary supplements covers a wide range of products including multivitamins, herbal supplements and energy drinks. High performance liquid chromatography (HPLC) is a common analytical technique for pharmaceuticals.
Taylor, Whitney Leigh, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source