Results 41 to 50 of about 321,144 (295)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Sports foods and dietary supplements for optimal function and performance enhancement in track and field athletes [PDF]

, 2009
Numerous nutritional products are marketed with claims of optimizing athlete health and function and/or enhancing performance. Products that fall under the banner of “Sports Foods” or “Dietary Supplements,” may be used to support performance during ...
Peeling, Peter, Castell, Linda M., Derave, Wim, de Hon, Olivier, Burke, Louise M.   +4 more
core   +1 more source

Review of nutrient actions on age-related macular degeneration [PDF]

, 2014
The actions of nutrients and related compounds on age-related macular degeneration (AMD) are explained in this review. The findings from 80 studies published since 2003 on the association between diet and supplements in AMD were reviewed.
Adams, Age-Related Eye Disease Study Research Group, Age-Related Eye Disease Study Research Group, Age-Related Eye Disease Study Research Group, Andrea Cusumano, Beatty, Berger, Bird, Boeing, Brantley, Chalam, Chen, Chiu, Chiu, Chiu, Chiu, Cho, Cho, Cho, Chong, Chong, Chong, Christen, Delcourt, Delyfer, Emiliano Giardina, Evans, Federico Ricci, Flood, Giardina, Giuseppe Novelli, Goldberg, Hennekens, Heuberger, Ho, Hodge, Hodge, Jacques, Jager, Jenkins, Johnson, Johnson, Kamburoglu, Klein, Klein, Kuzniarz, Lawrenson, Lepre, Loane, Lonn, Luigi Tonino Marsella, Ma, Ma, Mallal, Mares, Mares-Perlman, Mares-Perlman, Millen, Moriarty-Craige, Muir, Neale, Newsome, Newsome, Olin, Omenn, Parekh, Parekh, Ricci, Ricci, Robman, Rochtchina, Roth, SanGiovanni, Sangiovanni, Schreier, Seddon, Seddon, Seddon, Seddon, Selenium, Sin, Smith, Snodderly, Sommerburg, Stahl, Stefania Zampatti, Stocchi, Tan, Tsang, Uchiki, van Leeuwen, VandenLangenberg, Weikel, Wong, Woodside, Young   +95 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Centella asiatica and its caffeoylquinic acid and triterpene constituents increase dendritic arborization of mouse primary hippocampal neurons and improve age-related locomotion deficits in Drosophila

Frontiers in Aging
IntroductionCentella asiatica (CA) is known in Ayurvedic medicine as a rejuvenating herb with particular benefits in the nervous system. Two groups of specialized metabolites found in CA and purported to contribute to its beneficial effects are ...
Karon Rowe, Karon Rowe, Nora E. Gray, Nora E. Gray, Jonathan A. Zweig, Jonathan A. Zweig, Alexander Law, Alexander Law, Natascha Techen, Natascha Techen, Claudia S. Maier, Claudia S. Maier, Claudia S. Maier, Amala Soumyanath, Amala Soumyanath, Doris Kretzschmar, Doris Kretzschmar   +16 more
doaj   +1 more source

Dietary Supplement Labeling: Cognitive Biases, Market Manipulation & Consumer Choice [PDF]

, 2014
There exists increasing concern that the Dietary Supplements Health and Education Act (DSHEA) has proven ineffective. Much of the concern regards the disparity in legislative treatment between dietary supplements, foods, and pharmaceutical drugs. Namely,
McCann, Michael
core   +1 more source

Dietary Intake of Natural Sources of Docosahexaenoic Acid and Folate in Pregnant Women of Three European Cohorts [PDF]

, 2008
Background: Folic acid plays a fundamental role in cell division and differentiation. Docosahexaenoic acid (DHA) has been associated with infantile neurological and cognitive development.
Campoy, C., Decsi, Tamás, Dolz, V., Franke, Corinna, Koletzko, Berthold, Trak-Fellermeier, M., Verwied-Jorky, Sabine   +6 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Determination of Total Antioxidant Capacity in Saliva of Smokers and Non-smokers with Chronic Periodontitis

Bihdād, 2020
Background: Periodontal diseases in smokers are 2.6 to 6 times higher than non-smokers and their response to treatment is much lower. Reducing levels of antioxidants and consequently increasing oxidative damage in the pathogenesis of periodontitis is ...
Ahmadreza Mirzaei, Mahboobeh Mehrabani, Zohreh Khodaii, Hamid Mirshamsi, Nasrin Rafieian   +4 more
doaj  

FDA vs. Ephedra: Dietary Supplement Regulation Under DSHEA [PDF]

, 2012
The Dietary Supplement Health and Education Act of 1994 (DSHEA) dramatically changed the way dietary supplements are regulated in the United States. DSHEA created a new category of products defined as “dietary supplements,â€
Jones, Adam R.
core