Results 61 to 70 of about 840,652 (300)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Attitude toward dietary supplements among the subjects.

, 2023
Attitude toward dietary supplements among the subjects.
Khursheed Muzammil (12289621), Amani Alhazmi (562082), Sakeena Mushfiq (17138213), Beena Briget Kuriakose (17138210), Manal Mohammed Hawash (17138216)   +4 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Dietary Supplements in Dyslipidemia

, 2018
Lifestyle and dietary interventions can have a significant impact on patients with dyslipidemia and should be encouraged with the use of dietary supplements. With new research, there is evidence that using dietary supplements, specifically nutraceuticals
Emily Gutierrez, Yousef Elyaman
core   +1 more source

Multi-Omics Analysis in Mouse Primary Cortical Neurons Reveals Complex Positive and Negative Biological Interactions Between Constituent Compounds of Centella asiatica

Pharmaceuticals
Background: A water extract of the Ayurvedic plant Centella asiatica (L.) Urban, family Apiaceae (CAW), improves cognitive function in mouse models of aging and Alzheimer’s disease and affects dendritic arborization, mitochondrial activity, and oxidative
Steven R. Chamberlin, Jonathan A. Zweig, Cody J. Neff, Luke Marney, Jaewoo Choi, Liping Yang, Claudia S. Maier, Amala Soumyanath, Shannon McWeeney, Nora E. Gray   +9 more
doaj   +1 more source

Screening for impact of popular herbs improving mental abilities on the transcriptional level of brain transporters

Acta Pharmaceutica, 2014
There are a number of compounds that can modify the activity of ABC (ATP-binding cassette) and SLC (solute carrier) transporters in the blood-brain barrier (BBB).
Mrozikiewicz Przemyslaw M., Bogacz Anna, Bartkowiak-Wieczorek Joanna, Kujawski Radoslaw, Mikolajczak Przemyslaw L., Ozarowski Marcin, Czerny Boguslaw, Mrozikiewicz-Rakowska Beata, Grzeskowiak Edmund   +8 more
doaj   +1 more source

The relationship of supportive roles with mental health and satisfaction with life in female household heads in Karaj, Iran: a structural equations model

BMC Public Health, 2021
Background Female household heads are faced with more problems than men due to their multiple concurrent roles. The present study was conducted to determine the relationship of supportive roles with mental health and satisfaction with life in female ...
Nooshin Shadabi, Sara Esmaelzadeh Saeieh, Mostafa Qorbani, Touran Bahrami Babaheidari, Zohreh Mahmoodi   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The Use of Dietary Supplements Among African and Caribbean Women Living in the UK: A Cross-Sectional Study [PDF]

, 2020
Previous studies have shown that the use of dietary supplements is associated with the prevention of birth defects, negative pregnancy outcomes and cardiovascular diseases.
Amanda Rodrigues Amorim Adegboye, Adegboye, A.R.A., Amorim Adegboye, Amanda Rodrigues, Begum, Gulshanara, Ojo, O., Omorogieva Ojo, Gulshanara Begum, Ojo, Omorogieva, Begum, G.   +8 more
core   +1 more source