Results 21 to 30 of about 159,109 (263)

Allelic and Genotype Frequencies of CYP2B6∗2 (64C > T) and CYP2B6∗3 (777C > A) in Three Dominant Ethnicities of the Iranian Population

Genetics Research, 2023
Background. Cytochrome P450 complex plays a key role in drug metabolism. CYP2B6 has an essential part in Cytochrome P450 complex metabolism. This study aims to determine the allelic distribution of CYP2B6∗2 and CYP2B6∗3 in three main Iranian ethnicities:
Armin Khavandegar, Bahareh Tavakoli-Far, Sarina Ansari, Parisa Veis-Karami, Faezeh Ghasemi, Samira Sheibaninia, Roshanak Jazayeri, Massoud Houshmand   +7 more
doaj   +1 more source

Dietary supplements for dysmenorrhoea

Cochrane Database of Systematic Reviews, 2016
Dysmenorrhoea refers to painful menstrual cramps and is a common gynaecological complaint. Conventional treatments include non-steroidal anti-inflammatory drugs (NSAIDs) and oral contraceptive pills (OCPs), which both reduce myometrial activity (contractions of the uterus). A suggested alternative approach is dietary supplements.
Porjai, Pattanittum, Naowarat, Kunyanone, Julie, Brown, Ussanee S, Sangkomkamhang, Joanne, Barnes, Vahid, Seyfoddin, Jane, Marjoribanks   +6 more
openaire   +3 more sources

Botanicals in Dietary Supplements [PDF]

Evidence-Based Complementary and Alternative Medicine, 2013
Botanicals are accepted worldwide as medicinal agents and nutraceuticals. Extensive scientific investigations have been performed over the past 200 years which have resulted in the evolution of botanical utilization. This special issue highlights some of this research in 7 review articles and in 24 original research articles. Review Articles.
Weena Jiratchariyakul, Ludger Beerhues, Gail B. Mahady, Tanawan Kummalue, Molvibha Vongsakul   +4 more
openaire   +2 more sources

Peripheral Blood DNA Methylation Changes in Response to Centella asiatica Treatment in Aged Mice

Biology
Alterations in epigenetic modifications, like DNA methylation, in peripheral blood could serve as a useful, minimally invasive biomarker of the effects of anti-aging interventions.
Olivia Monestime, Brett A. Davis, Cora Layman, Kandace J. Wheeler, Wyatt Hack, Jonathan A. Zweig, Amala Soumyanath, Lucia Carbone, Nora E. Gray   +8 more
doaj   +1 more source

Amelioration of age-related cognitive decline and anxiety in mice by Centella asiatica extract varies by sex, dose and mode of administration

Frontiers in Aging
Background: A water extract (CAW) of the Ayurvedic plant Centella asiatica administered in drinking water has been shown to improve cognitive deficits in mouse models of aging and neurodegenerative diseases.
Nora E. Gray, Nora E. Gray, Wyatt Hack, Wyatt Hack, Mikah S. Brandes, Mikah S. Brandes, Jonathan A. Zweig, Jonathan A. Zweig, Liping Yang, Liping Yang, Luke Marney, Luke Marney, Jaewoo Choi, Jaewoo Choi, Armando Alcazar Magana, Armando Alcazar Magana, Natasha Cerruti, Natasha Cerruti, Janis McFerrin, Janis McFerrin, Seiji Koike, Seiji Koike, Thuan Nguyen, Thuan Nguyen, Jacob Raber, Jacob Raber, Joseph F. Quinn, Joseph F. Quinn, Joseph F. Quinn, Claudia S. Maier, Claudia S. Maier, Claudia S. Maier, Amala Soumyanath, Amala Soumyanath   +33 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Withania somnifera (Ashwagandha) Improves Spatial Memory, Anxiety and Depressive-like Behavior in the 5xFAD Mouse Model of Alzheimer’s Disease

Antioxidants
Withania somnifera (WS), also known as ashwagandha, is a popular botanical supplement used to treat various conditions including memory loss, anxiety and depression.
Noah Gladen-Kolarsky, Olivia Monestime, Melissa Bollen, Jaewoo Choi, Liping Yang, Armando Alcazar Magaña, Claudia S. Maier, Amala Soumyanath, Nora E. Gray   +8 more
doaj   +1 more source

Vaginal and oral probiotics effect in the prevention of preterm delivery in patients visiting Kamali Hospital, Karaj, Iran in 2020

European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 2022
Introduction: The prevalence of preterm labor (PTL) is growing, and annually one in ten babies is born prematurely. Various studies have examined the effect of oral or vaginal probiotics on the prevention of preterm labor, which has yielded contrasting ...
Elahe Solgi, Bahareh Tavakoli-Far, Bita Badehnoosh, Armin Khavandegar, Mahmood Bakhtiyari   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Liquid chromatography-mass spectrometry quantification of phytochemicals in Withania somnifera using data-dependent acquisition, multiple-reaction-monitoring, and parallel-reaction-monitoring with an inclusion list

Frontiers in Chemistry
Characterization of botanical extracts by mass spectrometry-based metabolomics analysis helps in determining the phytochemical composition that underlies their bioactivity and potential health benefits, while also supporting reproducibility of effects in
Luke C. Marney, Luke C. Marney, Jaewoo Choi, Jaewoo Choi, Armando Alcazar Magana, Armando Alcazar Magana, Armando Alcazar Magana, Liping Yang, Liping Yang, Natascha Techen, Natascha Techen, Md Nure Alam, Md Nure Alam, Mikah Brandes, Mikah Brandes, Amala Soumyanath, Amala Soumyanath, Jan F. Stevens, Jan F. Stevens, Jan F. Stevens, Claudia S. Maier, Claudia S. Maier, Claudia S. Maier   +22 more
doaj   +1 more source