Results 21 to 30 of about 840,652 (300)

Frequency of CYP2B6 Alleles in Major Iranian Ethnicities, Affecting Response to Efavirenz

Genetics Research, 2022
Introduction. Efavirenz is an antihuman immunodeficiency virus (HIV) drug metabolized by cytochrome P450 2B6 (CYP2B6) enzyme. Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene. Polymorphisms of this gene play a crucial role in
Parham Mardi, Bahareh Tavakoli-Far, Samira Sheibani Nia, Roshanak Jazayeri, Massoud Houshmand   +4 more
doaj   +1 more source

Dietary iron intake during early pregnancy and birth outcomes in a cohort of British women [PDF]

, 2011
Background: Iron deficiency during pregnancy is associated with adverse birth outcomes, particularly, if present during early gestation. Iron supplements are widely recommended during pregnancy, but evidence of their benefit in relation to infant ...
Greenwood, Darren C, Godfrey, KM, Simpson, NAB, J. E. Cade, McArdle, Harry J, D. C. Greenwood, Greenwood, Darren C., Alwan, NA, Simpson, Nigel A B, Greenwood, DC, Godfrey, Keith M, H. J. McArdle, McArdle, Harry J., Simpson, Nigel A.B., McArdle, HJ, K. M. Godfrey, Alwan, Nisreen A, Cade, Janet E, Cade, Janet E., Cade, JE, N. A. Alwan, N. A. B. Simpson, Alwan, Nisreen A., Godfrey, Keith M.   +23 more
core   +1 more source

Improving and Comparing Probiotic Plate Count Methods by Analytical Procedure Lifecycle Management

Frontiers in Microbiology, 2021
Probiotics are live microorganisms that confer a health benefit to the host when administered in adequate amounts. This definition links probiotic efficacy to microbial viability. The current gold standard assay for probiotic potency is enumeration using
M. L. Jane Weitzel, M. L. Jane Weitzel, Christina S. Vegge, Marco Pane, Virginia S. Goldman, Binu Koshy, Cisse Hedegaard Porsby, Pierre Burguière, Jean L. Schoeni   +8 more
doaj   +1 more source

Dietary Supplements and Stroke [PDF]

Mayo Clinic Proceedings, 2005
In the past, phenylpropanolamine (dl-norephedrine, an ephedrine alkaloid) was a common ingredient in appetite suppressants and cough and cold medicines. It has been associated with hypertension 1 and is an independent risk factor for hemorrhagic stroke in women.
Elizabeth S, McDonald, John I, Lane
openaire   +2 more sources

Breast cancer prevention with liquiritigenin from licorice through the inhibition of aromatase and protein biosynthesis in high-risk women’s breast tissue

Scientific Reports, 2023
Breast cancer risk continues to increase post menopause. Anti-estrogen therapies are available to prevent postmenopausal breast cancer in high-risk women. However, their adverse effects have reduced acceptability and overall success in cancer prevention.
Atieh Hajirahimkhan, Caitlin Howell, Elizabeth T. Bartom, Huali Dong, Daniel D. Lantvit, Xiaoling Xuei, Shao-Nong Chen, Guido F. Pauli, Judy L. Bolton, Susan E. Clare, Seema A. Khan, Birgit M. Dietz   +11 more
doaj   +1 more source

Are Dietary Supplements a Gateway to Doping? A Retrospective Survey of Athletes’ Substance Use

, 2023
: It is proposed that the use of dietary supplements might lead to the use of doping substances. This has been termed the gateway hypothesis. However, within an athletic sample, no research has examined the order in which these substances are consumed ...
Hurst, P.
core   +1 more source

Peripheral Blood DNA Methylation Changes in Response to Centella asiatica Treatment in Aged Mice

Biology
Alterations in epigenetic modifications, like DNA methylation, in peripheral blood could serve as a useful, minimally invasive biomarker of the effects of anti-aging interventions.
Olivia Monestime, Brett A. Davis, Cora Layman, Kandace J. Wheeler, Wyatt Hack, Jonathan A. Zweig, Amala Soumyanath, Lucia Carbone, Nora E. Gray   +8 more
doaj   +1 more source

Resveratrol as an Inhibitor of Pregnane X Receptor (PXR): Another Lesson in PXR Antagonism

Journal of Pharmacological Sciences, 2014
.: The pregnane X receptor (PXR) plays a central role in the regulation of metabolism. Only few PXR antagonists have been described and the mechanism of PXR inhibition is mostly hypothetical or believed to be allosteric.
Tomas Smutny, Petr Pavek
doaj   +1 more source

Allelic and Genotype Frequencies of CYP2B6∗2 (64C > T) and CYP2B6∗3 (777C > A) in Three Dominant Ethnicities of the Iranian Population

Genetics Research, 2023
Background. Cytochrome P450 complex plays a key role in drug metabolism. CYP2B6 has an essential part in Cytochrome P450 complex metabolism. This study aims to determine the allelic distribution of CYP2B6∗2 and CYP2B6∗3 in three main Iranian ethnicities:
Armin Khavandegar, Bahareh Tavakoli-Far, Sarina Ansari, Parisa Veis-Karami, Faezeh Ghasemi, Samira Sheibaninia, Roshanak Jazayeri, Massoud Houshmand   +7 more
doaj   +1 more source

Probiotic Bacteria and their Supernatants Protect Enterocyte Cell Lines from Enteroinvasive Escherichia coli (EIEC) Invasion [PDF]

International Journal of Molecular and Cellular Medicine, 2017
Probiotic microorganisms have attracted a growing interest for prevention and therapy of gastrointestinal disorders. Many probiotic strains have been shown to inhibit growth and metabolic activity of enteropathogenic bacteria as well as their adhesion ...
Zohreh Khodaii, Sayyed Mohammad Hossein Ghaderian, Mahboobeh Mehrabani Natanzi   +2 more
doaj