Results 21 to 30 of about 328,615 (242)

The safety of double- and triple-drug community mass drug administration for lymphatic filariasis: A multicenter, open-label, cluster-randomized study [PDF]

open access: yes, 2019
BackgroundThe Global Programme to Eliminate Lymphatic Filariasis (GPELF) provides antifilarial medications to hundreds of millions of people annually to treat filarial infections and prevent elephantiasis.
Bogus, Joshua   +7 more
core   +6 more sources

Diethylcarbamazine increases activation of voltage-activated potassium (SLO-1) currents in Ascaris suum and potentiates effects of emodepside. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
Diethylcarbamazine is a drug that is used for the treatment of filariasis in humans and animals; it also has effects on intestinal nematodes, but its mechanism of action remains unclear.
Samuel K Buxton   +2 more
doaj   +1 more source

Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Cote d\u27Ivoire [PDF]

open access: yes, 2019
BackgroundA single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used ...
Bjerum, Catherine M   +9 more
core   +4 more sources

Dosing pole recommendations for lymphatic filariasis elimination: A height-weight quantile regression modeling approach [PDF]

open access: yes, 2019
BACKGROUND: The World Health Organization (WHO) currently recommends height or age-based dosing as alternatives to weight-based dosing for mass drug administration lymphatic filariasis (LF) elimination programs.
Dubray, Christine   +14 more
core   +2 more sources

Mass drug administration coverage evaluation survey for lymphatic Filariasis in Bagalkot and Gulbarga districts

open access: yesIndian Journal of Community Medicine, 2012
Background: Lymphatic filariasis (LF) is endemic in 83 countries and territories, with more than a billion people at risk of infection. In view with the global elimination, mass drug administration (MDA) with single dose of diethylcarbamazine and ...
Prakash Kurubarahalli Patel
doaj   +1 more source

Lymphatic Filariasis Control in Tanzania: Effect of Six Rounds of Mass Drug Administration with Ivermectin and Albendazole on Infection and Transmission. [PDF]

open access: yes, 2013
Control of lymphatic filariasis (LF) in most countries of sub-Saharan Africa is based on annual mass drug administration (MDA) with a combination of ivermectin and albendazole, in order to interrupt transmission. We present findings from a detailed study
C Chaccour   +48 more
core   +1 more source

Comparison of different drug regimens for the treatment of loiasis-A TropNet retrospective study. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2018
BACKGROUND:Loa loa infection is endemic in limited areas of West-Central Africa. Loiasis has been associated with excess mortality, but clinical studies on its treatment are scant, particularly outside endemic areas, due to the rarity of cases diagnosed.
Federico Gobbi   +16 more
doaj   +1 more source

Efficacy of High-Dose Albendazole with Ivermectin for Treating Imported Loiasis, Italy

open access: yesEmerging Infectious Diseases, 2019
We describe the outcomes of 16 cases of imported loiasis in Italy. Patients had microfilaremia
Federico Gobbi   +5 more
doaj   +1 more source

Genital filariasis presenting as a vaginal wall cystic lesion

open access: yesIDCases, 2020
Vaginal cystic lesions are rare incidental findings detected during physical examination and imaging. To our knowledge, filariasis as a cause of vaginal cystic lesions has not been previously reported in the English literature.
Prasanna Ghimire, Pragya Gautam Ghimire
doaj   +1 more source

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