Potential value of triple drug therapy with ivermectin, diethylcarbamazine, and albendazole (IDA) to accelerate elimination of lymphatic filariasis and onchocerciasis in Africa [PDF]
, 2017 BACKGROUND: The success of programs to eliminate lymphatic filariasis (LF) depends in large part on their ability to achieve and sustain high levels of compliance with mass drug administration (MDA). This paper reports results from a comprehensive review
Fischer, Peter U +3 more
core +22 more sources
The safety of double- and triple-drug community mass drug administration for lymphatic filariasis: A multicenter, open-label, cluster-randomized study [PDF]
, 2019 BackgroundThe Global Programme to Eliminate Lymphatic Filariasis (GPELF) provides antifilarial medications to hundreds of millions of people annually to treat filarial infections and prevent elephantiasis.
Bogus, Joshua +7 more
core +6 more sources
Tetracycline Resistance Pattern Among Lymphatic Filariasis-Hyperendemic Communities in Southern Ghana: A Mixed-Method Approach. [PDF]
Health Sci RepABSTRACT Background and Aim Tetracyclines continue to serve as a cost‐effective and essential treatment for common infections, particularly in resource‐limited regions such as lymphatic filariasis (LF)‐hyperendemic communities. The growing use of tetracycline‐based antibiotics by symptomatic filarial lymphedema patients, likely influenced by the ...
Osei-Poku P +7 more
europepmc +2 more sources
Diethylcarbamazine increases activation of voltage-activated potassium (SLO-1) currents in Ascaris suum and potentiates effects of emodepside. [PDF]
PLoS Neglected Tropical Diseases, 2014 Diethylcarbamazine is a drug that is used for the treatment of filariasis in humans and animals; it also has effects on intestinal nematodes, but its mechanism of action remains unclear.
Samuel K Buxton +2 more
doaj +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2022 Diethylcarbamazine-loaded nanoparticles were previously evaluated for their anti-inflammatory activity. However, little is known regarding their physicochemical properties.
Henrique Rodrigues Marcelino +8 more
doaj +1 more source
Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Cote d\u27Ivoire [PDF]
, 2019 BackgroundA single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used ...
Bjerum, Catherine M +9 more
core +4 more sources
Indian Journal of Community Medicine, 2012 Background: Lymphatic filariasis (LF) is endemic in 83 countries and territories, with more than a billion people at risk of infection. In view with the global elimination, mass drug administration (MDA) with single dose of diethylcarbamazine and ...
Prakash Kurubarahalli Patel
doaj +1 more source
Comparison of different drug regimens for the treatment of loiasis-A TropNet retrospective study. [PDF]
PLoS Neglected Tropical Diseases, 2018 BACKGROUND:Loa loa infection is endemic in limited areas of West-Central Africa. Loiasis has been associated with excess mortality, but clinical studies on its treatment are scant, particularly outside endemic areas, due to the rarity of cases diagnosed.
Federico Gobbi +16 more
doaj +1 more source
Efficacy of High-Dose Albendazole with Ivermectin for Treating Imported Loiasis, Italy
Emerging Infectious Diseases, 2019 We describe the outcomes of 16 cases of imported loiasis in Italy. Patients had microfilaremia
Federico Gobbi +5 more
doaj +1 more source
Genital filariasis presenting as a vaginal wall cystic lesion
IDCases, 2020 Vaginal cystic lesions are rare incidental findings detected during physical examination and imaging. To our knowledge, filariasis as a cause of vaginal cystic lesions has not been previously reported in the English literature.
Prasanna Ghimire, Pragya Gautam Ghimire
doaj +1 more source