Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis [PDF]
Lymphatic filariasis and onchocerciasis are parasitic helminth diseases, which cause severe morbidities such as elephantiasis, skin disease and blindness, presenting a major public health burden in endemic communities.
Aljayyoussi, Ghaith +17 more
core +3 more sources
Aim. Onchocerciasis is an endemic parasitic disease in sub‐Saharan Africa that significantly impacts animal and human health. In Northern Cameroon, medicinal plants from the Combretum genus are used for onchocerciasis traditional treatment although there is no scientific evidence of their antifilarial potential. This study evaluates the in vitro macro‐
Banserne Brey Ignagali +5 more
wiley +1 more source
Treatment of the microfilaraemia of asymptomatic brugian filariasis with single doses of ivermectin, diethylcarbamazine or albendazole, in various combinations [PDF]
Several new chemotherapeutic tools are now available for the control of lymphatic filariasis. Combinations of single doses of antifilarial drugs are generally superior to single drugs.
Dalia, S +4 more
core
Lymphatic filariasis is a leading cause of chronic and irreversible damage to human immunity. This paper presents deterministic and continuous‐time Markov chain (CTMC) stochastic models regarding lymphatic filariasis dynamics. To account for randomness and uncertainties in dynamics, the CTMC model was formulated based on deterministic model possible ...
Mussa A. Stephano +4 more
wiley +1 more source
An investigation of the disparity in estimates of microfilaraemia and antigenaemia in lymphatic filariasis surveys [PDF]
The diagnosis of lymphatic filariasis (LF) is based typically on either microfilaraemia as assessed by microscopy or filarial antigenaemia using an immuno-chromatographic test.
Bockarie, Moses J +8 more
core +6 more sources
Wolbachia and Lymphatic Filarial Nematodes and Their Implications in the Pathogenesis of the Disease
Lymphatic filariasis (LF) is an infection of three closely related filarial worms such as Wuchereria bancrofti, Brugia malayi, and Brugia timori. These worms can cause a devastating disease that involves acute and chronic lymphoedema of the extremities, which can cause elephantiasis in both sexes and hydroceles in males.
Abebaw Setegn +3 more
wiley +1 more source
Side Effects following School Deworming among School‐Age Children in Oti Region, Ghana
Background. Preventive chemotherapy with anthelminthic drugs is meant to control soil‐transmitted helminthiases, but some children may experience adverse reactions. Objective. This study investigated why some school‐age children did not receive the medication as well as the side effects experienced by those who did during the 2019 preventive ...
Jean Claude Romaric Pingdwindé Ouédraogo +2 more
wiley +1 more source
A 46-year-old male presented with best corrected visual acuity (BCVA) of 20/125 in his right eye. Fundus showed disc edema, multiple yellow outer retinal crops, macular edema and a live motile worm in the subretinal space. Diagnosis of diffuse unilateral
Navya Cherukuri +4 more
doaj +1 more source
Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19? [PDF]
Anuruddha M Abeygunasekera +1 more
openalex +1 more source
A large filarial hydrocele in Kenya: a case report
Morbidity Management and Disability Prevention (MMDP) remains a key aspect of the Global project for the Elimination of Lymphatic Filariasis (GPELF) a program launched by WHO in the year 2000.
Charles Waihenya +2 more
doaj +1 more source

