Results 61 to 70 of about 334,424 (174)

A comparison of the efficacy of single doses of albendazole, ivermectin, and diethylcarbamazine alone or in combinations against Ascaris and Trichuris spp.

Bulletin of the World Health Organization, 2003
OBJECTIVE: To determine the efficacy of single doses of albendazole, ivermectin and diethylcarbamazine, and of the combinations albendazole + ivermectin and albendazole + diethylcarbamazine against common intestinal helminthiases caused by Ascaris and ...
Belizario V.Y., Amarillo M.E., Leon W.U. de, Reyes A.E. de los, Bugayong M.G., Macatangay B.J.C.   +5 more
doaj  

Emerging connectivity of programmed cell death pathways and pulmonary vascular remodelling during pulmonary hypertension

Journal of Cellular and Molecular Medicine, Volume 28, Issue 16, August 2024.
Abstract Pulmonary hypertension (PH) is a chronic progressive vascular disease characterized by abnormal pulmonary vascular resistance and pulmonary artery pressure. The major structural alteration during PH is pulmonary vascular remodelling, which is mainly caused by the imbalance between proliferation and apoptosis of pulmonary vascular cells ...
Meng‐nan Yuan, Ting Liu, An‐qi Cai, Zibo Zhan, Yi‐li Cheng, Qi‐yue Wang, Yu‐xuan Xia, Nong‐er Shen, Ping Huang, Xiao‐zhou Zou   +9 more
wiley   +1 more source

What is the role of microbial biotechnology and genetic engineering in medicine?

MicrobiologyOpen, Volume 13, Issue 2, April 2024.
Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
wiley   +1 more source

Diagnosis of O. volvulus infection via skin exposure to diethylcarbamazine: clinical evaluation of a transdermal delivery technology-based patch

Parasites & Vectors, 2015
Background Elimination of onchocerciasis in Africa is now regarded as an achievable goal in many areas. This makes monitoring changes in infection prevalence a key component of control programmes. Monitoring is currently based on determining the presence
K. Awadzi, Nicholas O. Opoku, Simon K. Attah, Janis K. Lazdins-Helds, Annette C. Kuesel   +4 more
doaj   +1 more source

Isolated perinephric abscess as the initial manifestation of filariasis—an unusual presentation

Clinical Case Reports, Volume 12, Issue 3, March 2024.
Graphical Abstract Key Clinical Message Filariasis may present as an isolated perinephric abscess. Hence, a high index of suspicion should be maintained in endemic settings. Abstract In cases with unexplained fever, eosinophilia and perinephric collection, it is necessary to do detailed infectious disease work up. High index of suspicion is required to
Govind Sharma, Rajat Sachdeva, Shweta Aggarwal, Amogh Verma, Ayush Anand, Ajeet Singh, Prakasini Satapathy   +6 more
wiley   +1 more source

Role of PASCAL and optical coherence tomography angiograpgy in the treatment of diffuse unilateral subacute neuroretinitis caused by large live motile worm

Indian Journal of Ophthalmology, 2019
A 46-year-old male presented with best corrected visual acuity (BCVA) of 20/125 in his right eye. Fundus showed disc edema, multiple yellow outer retinal crops, macular edema and a live motile worm in the subretinal space. Diagnosis of diffuse unilateral
Navya Cherukuri, Bhavik Panchal, Hrishikesh Kaza, Shreyansh Doshi, Avinash Pathengay   +4 more
doaj   +1 more source

A large filarial hydrocele in Kenya: a case report

Frontiers in Tropical Diseases
Morbidity Management and Disability Prevention (MMDP) remains a key aspect of the Global project for the Elimination of Lymphatic Filariasis (GPELF) a program launched by WHO in the year 2000.
Charles Waihenya, Sheila Githui, Edgard Schouame   +2 more
doaj   +1 more source

Vector control complements mass drug administration against bancroftian filariasis in Tirukoilur, India

Bulletin of the World Health Organization, 2007
OBJECTIVE: To determine the role of vector control in further decreasing the transmission of bancroftian filariasis achieved by mass drug administration and the long-term impact on filariometric indices.
IP Sunish, R Rajendran, TR Mani, A Munirathinam, AP Dash, BK Tyagi   +5 more
doaj  

Diethylcarbamazine Attenuates the Development of Carrageenan-Induced Lung Injury in Mice

Mediators of Inflammation, 2014
Diethylcarbamazine (DEC) is an antifilarial drug with potent anti-inflammatory properties as a result of its interference with the metabolism of arachidonic acid.
Edlene Lima Ribeiro, Karla Patricia de Souza Barbosa, Ingrid Tavares Fragoso, Mariana Aragão Matos Donato, Fabiana Oliveira dos Santos Gomes, Bruna Santos da Silva, Amanda Karolina Soares e Silva, Sura Wanessa Santos Rocha, Valdemiro Amaro da Silva Junior, Christina Alves Peixoto   +9 more
doaj   +1 more source

Diethylcarbamazine and Non-Diethylcarbamazine Related Bancroftian Granuloma: An Immunohistochemical Study of Eosinophil Toxic Proteins

International Journal of Biomedical Science, 2010
It has been suggested, mostly using in vitro experiments, that defenses against parasites involve mainly activated eosinophils and their toxic proteins, such as major basic protein (MBP), eosinophil cationic protein (ECP) and eosinophil peroxidase (EPO).
Jose, Figueredo-Silva, Carmelita, Cavalcanti, Luciano Tavares, Montenegro, Joaquim, Norões, Gerusa, Dreyer   +4 more
openaire   +2 more sources