Results 61 to 70 of about 334,286 (214)

Acute tropical pulmonary eosinophilia: characterization of the lower respiratory tract inflammation and its response to therapy [PDF]

, 1987
Although acute tropical pulmonary eosinophilia (TPE) is well recognized as a manifestation of filarial infection, the processes that mediate the abnormalities of the lung in TPE are unknown.
Cornelius, Mary J, Crystal, Ronald G, Ferrans, V J, Kumaraswami, V, Nutman, T B, O'Donnell, Kathleen M, Ottesen, E A, Pinkston, Paula, Rom, William N, Takemura, T, Thiruvengadam, K V, Tripathy, S P, Vijayan, V K, Yenokida, Gordon   +13 more
core   +1 more source

Systematic review of the evidence for treatment and management of common skin conditions in resource‐limited settings: An update

Tropical Medicine &International Health, Volume 29, Issue 11, Page 923-950, November 2024.
Abstract Introduction The skin is the largest and most visible organ of the human body. As such, skin infections can have a significant impact on overall health, social wellbeing and self‐image. In 2019, we published a systematic review of the treatment, prevention and public health control of skin infections including impetigo, scabies, crusted ...
Ingrid Amgarth‐Duff, Hannah Thomas, Bernadette M. Ricciardo, Lorraine Anderson, Mike Stephens, Bart J. Currie, Andrew C. Steer, Steven Y. C. Tong, Kristy Crooks, Allison Hempenstall, Artiene Tatian, Rachel Foster, George Kavalam, Tharushi Pallegedara, Kennedy Walls, Asha Bowen   +15 more
wiley   +1 more source

Effects of rifampicin and ketoconazole on the pharmacokinetics of a single oral dose of diethylcarbamazine in healthy volunteers

Journal of Health Science and Medical Research (JHSMR), 2006
Diethylcarbamazine (DEC) is the first-line drug for the control and treatment of lymphatic filariasis caused by the Wuchereria bancrofti and Brugia malayi parasite. DEC is rapidly and extensively metabolised in the liver.
W Ridtitid, M Wongnawa, W Mahatthanatrakul, A Pattanawongsa, N Bumrungwong, M Sunbhanich   +5 more
doaj  

Mass Drug Administration and beyond: how can we strengthen health systems to deliver complex interventions to eliminate neglected tropical diseases? [PDF]

, 2015
Achieving the 2020 goals for Neglected Tropical Diseases (NTDs) requires scale-up of Mass Drug Administration (MDA) which will require long-term commitment of national and global financing partners, strengthening national capacity and, at the community ...
Adams, ER, Bockarie, MJ, Harrison, RA, Hollingsworth, T, Kelly-Hope, LA, Kovacic, V, Lehane, M, Macpherson, EE, Paine, MJI, Reimer, LJ, Torr, SJ   +10 more
core   +1 more source

A Phase 1, Randomized, Double‐Blind, Placebo‐Controlled, Single Ascending Dose Trial of AWZ1066S, an Anti‐Wolbachia Candidate Macrofilaricide

Clinical Pharmacology in Drug Development, Volume 13, Issue 9, Page 1071-1081, September 2024.
Abstract AWZ1066S has been developed as a potential treatment for the neglected tropical diseases lymphatic filariasis and onchocerciasis. AWZ1066S targets the Wolbachia bacterial endosymbiont present in the causative nematode parasites. This phase 1, first‐in‐human study aimed to assess the safety and pharmacokinetics of AWZ1066S in healthy human ...
Graham Devereux, Marcin Bula, Karen Tripp, Richard Fitzgerald, Nicola Eraut, Muhammad Salman Alam, Tomoyuki Moriyama, Raku Shinkyo, Lauren Walker, Duolao Wang, Fabian Gusovsky, Jeannette van der Velde, Joseph D. Turner, Weiqian David Hong, Paul M. O'Neill, Mark J. Taylor, Stephen A. Ward   +16 more
wiley   +1 more source

Situasi Filariasis di Pulau Alor pada Tahun 2006 [PDF]

, 2010
Background: In Alor District, a mass drug treatment using diethylcarbamazine citrat and albendazole has been done since 2002 by Alor District Health Office (DHO).
Ekowatiningsih, R. (Ryanti), Manumpil, P. (Paul), Sismadi, P. (Prijanto), Tuti, S. (Sekar)   +3 more
core  

Mathematical modelling of lymphatic filariasis elimination programmes in India: Required duration of mass drug administration and post-treatment level of infection indicators [PDF]

, 2016
Background: India has made great progress towards the elimination of lymphatic filariasis. By 2015, most endemic districts had completed at least five annual rounds of mass drug administration (MDA).
A Krentel, AD Hopkins, AN Shriram, AP Plaisier, AP Plaisier, BK Chu, BK Singh, BK Singh, BV Babu, Chellasamy Vinubala, CM Stone, D Das, E Michael, E Michael, E Michael, E Michael, E Michael, EA Ottesen, EA Ottesen, FO Richards Jr, G Dreyer, G Pichon, GJ Weil, GJ Weil, GJ Weil, GJ Weil, GJ Weil, H Slater, HP Duerr, HP Duerr, IP Sunish, IP Sunish, IP Sunish, J Cano, JB Koroma, JDF Habbema, K Gass, K Polman, L Nicolas, LC Snow, M El Setouhy, M Gambhir, M Gambhir, M Gyapong, MA Hussain, MA Irvine, MC Stanton, MEA De Kraker, MG Basáñez, N Bhullar, NA Kshirsagar, NL Nguyen, P Vanamail, PN Okorie, Purushothaman Jambulingam, R Gounoue-Kamkumo, S Chanteau, S Ghosh, S Sabesan, S Sabesan, S Subramanian, S Subramanian, S Subramanian, S Swaminathan, S. J. de Vlas, SP Pani, SW Lindsay, Swaminathan Subramanian, TC Yahathugoda, TD Hollingsworth, U Amazigo, W. A. Stolk, WA Stolk, WA Stolk, WA Stolk, WA Stolk, WA Stolk, WA Stolk, WA Stolk, WA Stolk, WHO Regional Office for South-East Asia, World Health Organization, World Health Organization, World Health Organization, WR Brieger   +84 more
core   +7 more sources

Emerging connectivity of programmed cell death pathways and pulmonary vascular remodelling during pulmonary hypertension

Journal of Cellular and Molecular Medicine, Volume 28, Issue 16, August 2024.
Abstract Pulmonary hypertension (PH) is a chronic progressive vascular disease characterized by abnormal pulmonary vascular resistance and pulmonary artery pressure. The major structural alteration during PH is pulmonary vascular remodelling, which is mainly caused by the imbalance between proliferation and apoptosis of pulmonary vascular cells ...
Meng‐nan Yuan, Ting Liu, An‐qi Cai, Zibo Zhan, Yi‐li Cheng, Qi‐yue Wang, Yu‐xuan Xia, Nong‐er Shen, Ping Huang, Xiao‐zhou Zou   +9 more
wiley   +1 more source

What is the role of microbial biotechnology and genetic engineering in medicine?

MicrobiologyOpen, Volume 13, Issue 2, April 2024.
Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
wiley   +1 more source

Incidental Detection Microfilaria in Subcutaneous Breast Nodule of Lactating Female Fnac: A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2014
Filariasis is a major public health problem which is faced in tropical countries like India. Its diagnosis is made by using peripheral blood smears. However, microfilaria has been detected incidentally during FNACs of various lesions, which were done in
Ajay KR. Singh, Prashant Gupta, Soma Yadav, H.S. Pahawa   +3 more
doaj   +1 more source