Results 281 to 290 of about 59,897 (352)

Beyond the patient: how providers perceive and experience non-medical barriers in gastrointestinal cancer care. [PDF]

Support Care Cancer
Lal T, Moody D, Chiratanagandla R, Meehan G, Davey CH, Bora S, Stange K, Hoehn RS.   +7 more
europepmc   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Enteral feeding barriers in the intensive care unit of a tertiary hospital in Ghana. [PDF]

South Afr J Crit Care
Anku EK, Hill LT, Agyarko MA, Ekor OE, Akafity G, Amoo SA, Lamptey SO, Kumi N.   +7 more
europepmc   +1 more source

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

The role of outcome expectancies and social support in adherence to nutrition counseling: perspectives of Emirati adults with diabetes. [PDF]

Front Public Health
Ali HI, Al Harbi AI, Alnahdi M, Alshamsi MS, Aldhaheri MR, Al Meqbaali SM, Aldahmani MA, Fatima N, Shahbaz HM, Bataineh MF.   +9 more
europepmc   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Letter: Lost in Translation-Replicating a Modifying FODMAP Diet in Patients With IBS. [PDF]

Aliment Pharmacol Ther
Halmos EP, Gibson PR.
europepmc   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Nutrition Care Practices in Colorectal Cancer: A National Survey of Patients, Caregivers, and Healthcare Professionals in Canada. [PDF]

Curr Oncol
Karry IM, Chung SS, Stein BD, Graifer O, Ford KL, Jagoe RT, Fillion M, More K, Bassett-Saltarelli N, Chon J, Leon N, Asmis TR, Chasen M.   +12 more
europepmc   +1 more source

Low-FODMAP Diet for Gastrointestinal Symptoms in Endometriosis: A Systematic Review. [PDF]

Nutrients
Watrowski R, Kostov S, Schäfer SD, Juhasz-Böss I, Palumbo M, Sparić R, Mereu L, Vitale SG, Alkatout I.   +8 more
europepmc   +1 more source