Results 171 to 180 of about 8,209,000 (311)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Sexual difference: masculinity and psychoanalysis

open access: yes, 1994
Book synopsis: Sexual Difference is a critical exploration of psychoanalytic theories of sexual difference. In particular it explores the way in which masculinity is expressed in theory and practice.
Frosh, Stephen
core  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Bacterial Diversity in Leaf-Cutter Ant Species: Host-Microbe Interactions and Environmental Effects. [PDF]

open access: yesNeotrop Entomol
Gianaris A   +5 more
europepmc   +1 more source

"Wood with a Difference" und "Drawn in Sand" - unrealisierte Werke von Alvar Aalto

open access: yes, 2009
Eröffnung der Doppelausstellung "Drawn in Sand - unrealisierte Werke von Alvar Aalto" und "Wood with a Difference" (Kuratoren D.Kuhlmann, Kari ...
Kuhlmann, Dörte, Jormakka, Kari
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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