Results 81 to 90 of about 168,585,035 (181)

A Pilot Survey of Indian Stakeholders: Parents, Doctors, and Grown-Up Patients of Disorders of Sexual Differentiation on Management Decisions and Associated Gender Dysphoria

Journal of Indian Association of Pediatric Surgeons
Background and Aims: Of late, there are many legal representations from select quarters to halt all medical interventions in children with differences of sex development (DSD).
Simmi K. Ratan, Sujoy Neogi, Md Fahim Ahmad, Kanishka Das, Vijaya Raman, Pradnya S. Bendre, Arka Banerjee, Shilpa Sharma, Himanshu Acharya, Vikesh Agrawal, Ramesh Babu   +10 more
doaj   +1 more source

Determining the Minimal Clinically Important Difference of the 40‐Item Smell Identification Test in People With Cystic Fibrosis

International Forum of Allergy &Rhinology, Volume 16, Issue 9, Page 924-930, September 2026.
ABSTRACT Background Chronic rhinosinusitis (CRS) and olfactory dysfunction (OD) are highly prevalent among people with cystic fibrosis (PwCF) and negatively impact quality of life. The 40‐item Smell Identification Test (SIT) is widely used to assess psychophysical olfaction, but a CF‐specific minimal clinically important difference (MCID) has not been ...
Eugene Oh, Jessa E. Miller, Michelle J. Lee, Anna Zemke, David Baraghoshi, Matthew J. Strand, Jeremiah A. Alt, Todd E. Bodner, Michael Chang, Naweed I. Chowdhury, Patricia H. Eshaghian, Anne E. Getz, Jennifer L. Goralski, David A. Gudis, Peter H. Hwang, Ashoke Khanwalkar, Adam J. Kimple, Jivianne T. Lee, Douglas A. Li, Jess C. Mace, Jayakar V. Nayak, Jonathan B. Overdevest, Zara Patel, Daniella K. Safatian, Rodney J. Schlosser, Brent Senior, Amanda L. Stapleton, Timothy L. Smith, Zachary M. Soler, Jeffrey D. Suh, Grant A. Turner, Marilene B. Wang, Milene T. Saavedra, Jennifer L. Taylor‐Cousar, Daniel M. Beswick   +34 more
wiley   +1 more source

A Likely Diagnosis of Familial Partial Androgen Insensitivity Syndrome in Three 46, XY Siblings With Ambiguous Genitalia: A Case Series

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Familial partial androgen insensitivity syndrome is a rare cause of 46, XY disorder of sex development. It includes marked phenotypic variability, even among siblings. Persistent undervirilization despite normal androgen levels should prompt early multidisciplinary evaluation and counseling, especially where genetic testing is limited.
Tayyeb Ali, Muhammad Hassaan Javaid, Sibgha Fawad Memon, Zauha Fawad Memon, Munazza Iqbal, Sadia Afridi, Abdul Rahim Soroush, Adnan Iqbal Khan, Naseer Ahmad, Nayab Ayub Afridi, Zuhaib Ali   +10 more
wiley   +1 more source

The risk of mental disorders in patients with disorders/differences of sex differentiation/development (DSD) and Y chromosome

Endokrynologia Polska, 2020
Patients with disorders/differences of sex differentiation/development (DSD) are exposed to physical and mental suffering. The aim of the study was to assess the following: the mental health status and the risk of mental problems in adult DSD patients, their dependence on therapeutic procedures, and to identify groups of disorders that require ...
Katarzyna, Bajszczak, Maria, Szarras-Czapnik, Renata, Walczak-Jędrzejowska, Katarzyna, Marchlewska, Jolanta, Slowikowska-Hilczer   +4 more
openaire   +3 more sources

Standardised data collection for clinical follow-up and assessment of outcomes in differences of sex development (DSD): recommendations from the COST action DSDnet [PDF]

, 2019
The treatment and care of individuals who have a difference of sex development (DSD) have been revised over the past two decades and new guidelines have been published.
Ahmed, S Faisal, COST Action BM1303 Working Grp, _, Springer, Alexander, Köhler, Birgit, Berra, Marta, Schweizer, Katinka, Cools, Martine, Ahmed, S. Faisal, Hall, Joanne, Hiort, Olaf, Westerveld, Puck, Pasterski, Vickie, Robeva, Ralitsa, Flück, Christa, Ali, Salma R., Nordenström, Anna, Ali, Salma R   +16 more
core   +2 more sources

Reproducibility of Serum Androgen Concentrations by Liquid Chromatography Mass Spectrometry in Healthy Male and Female Athletes

Drug Testing and Analysis, Volume 18, Issue 9, Page 1220-1224, September 2026.
Box and whiskers plots show the distributions of serum testosterone (T), dihydrotestosterone (DHT), androstenedione (A4), and the ratios of T/FDHT and T/A4. ABSTRACT Detection of androgen doping relies on mass spectrometry‐based methods to detect natural endogenous and exogenous androgens in urine and serum. To distinguish exogenous administration from
D. J. Handelsman, S. Bermon
wiley   +1 more source

Seasonal dynamism or model realism: What drives better predictions of landscape connectivity?

Ecosphere, Volume 17, Issue 9, September 2026.
Abstract Connectivity modeling is central to conservation science, yet most studies assume static landscapes and fixed species‐habitat preferences, thus overlooking seasonal dynamics. Additionally, many rely on simplistic species‐habitat associations rather than realistic movement models that mechanistically capture animal behavior.
David D. Hofmann, Dominik M. Behr, John W. McNutt, Arpat Ozgul, Gabriele Cozzi   +4 more
wiley   +1 more source

Overexpression of SOX3 due to an X chromosome inversion leading to ovotesticular difference in sex development

Biology of Sex Differences
Structural variants (SVs) may increase SOX3 expression in the gonads and have been observed in individuals with ovotesticular differences in sex development (OT-DSD) and XX testicular differences in sex development (T-DSD).
Carolina Gama Nascimento-Vidoti, Helena Fabbri-Scallet, Mara Sanches Guaragna, Melissa Bittencourt de Wallau, Vanessa Sodré de Souza, Silvia Souza da Costa, Ana Cristina Victorino Krepischi, Juliana Forte Mazzeu, Claudia M. B. Carvalho, Andréa Trevas Maciel-Guerra, Gil Guerra-Júnior, Társis Paiva Vieira   +11 more
doaj   +1 more source

Disorders of sex development expose transcriptional autonomy of genetic sex and androgen-programmed hormonal sex in human blood leukocytes

BMC Genomics, 2009
Background Gender appears to be determined by independent programs controlled by the sex-chromosomes and by androgen-dependent programming during embryonic development.
Appari Mahesh, Cario Gunnar, Richter-Unruh Annette, Demeter Janos, Werner Ralf, Bebermeier Jan-Hendrik, Holterhus Paul-Martin, Siebert Reiner, Riepe Felix, Brooks James D, Hiort Olaf   +10 more
doaj   +1 more source

46,XX Differences of Sex Development outside congenital adrenal hyperplasia: pathogenesis, clinical aspects, puberty, sex hormone replacement therapy and fertility outcomes

Frontiers in Endocrinology
The term ‘differences of sex development’ (DSD) refers to a group of congenital conditions that are associated with atypical development of chromosomal, gonadal, and/or anatomical sex.
Marianna Rita Stancampiano, Silvia Laura Carla Meroni, Carmen Bucolo, Gianni Russo   +3 more
doaj   +1 more source