Results 71 to 80 of about 168,585,035 (181)

46,XY disorders of sex development (DSD)

, 2009
The term disorders of sex development (DSD) includes congenital conditions in which development of chromosomal, gonadal or anatomical sex is atypical.
MENDONCA, Berenice Bilharinho, ARNHOLD, Ivo J. P., COSTA, Elaine M. F., DOMENICE, Sorahia   +3 more
core   +1 more source

Case Report: De novo DHX37 mutations in Saudi patients with 46,XY differences of sex development

Frontiers in Endocrinology
Differences of sex development (DSD) are a group of congenital conditions involving atypical chromosomal, gonadal, or anatomical sex development. DHX37, a gene involved in ribosome biogenesis, located on chromosome 12, at the 12q24.31 region, has ...
Abeer Alabduljabbar, Sara Abid, Dania Farooq, Sara Aljazaeri, Yara Khamag, Raghad Alhuthil, Latifah Alfahad, Afaf Alsagheir, Afaf Alsagheir   +8 more
doaj   +1 more source

An Effective Machine Learning for Prioritizing Hearing Loss Screening in Older Adults: A Primary Care Approach

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background/Objectives The high prevalence of hearing impairment in older adults and the scarcity of diagnostic resources in primary health care (PHC) highlight the need for solutions based on artificial intelligence. This study aimed to develop and evaluate a decision tree model to prioritize hearing examinations in this population. Methods An
Simone Seixas da Cruz, Edilson José Rodrigues, Michelle de Santana Xavier Ramos, Débora Conceição Santos de Oliveira, Paulo José dos Santos de Matos, Julita Maria Freitas Coelho, Dóris Firmino Rabelo, Alexandre Marcelo Hintz, Johelle Santana Passos‐Soares, Ana Claudia Morais Godoy Figueiredo, Isaac Suzart Gomes‐Filho   +10 more
wiley   +1 more source

Clinical practice guidelines for the management of differences of sex development in Japan

Endocrine Journal
Differences of sex development (DSD) are congenital conditions in which chromosomal, gonadal, and anatomical sex characteristics are discordant with typical male or female development.
Tomohiro Ishii, Kenichi Kashimada, Masanobu Kawai, Tomoyo Itonaga, Takeshi Iwasa, Akari Utsunomiya, Kayo Ozaki, Kazuhiro Kawamura, Junko Kanno, Jun Koh, Yoshiyuki Kojima, Shoko Sasaki, Hiroyuki Sato, Koji Shiraishi, Yasuhiro Naiki, Mitsuru Nishiyama, Takashi Hamajima, Yasuko Fujisawa, Noriko Makita, Katsuyuki Matsui, Toshihiro Yanai, Reiko Horikawa, Tsutomu Ogata   +22 more
doaj   +1 more source

First Report of Enterocytozoon bieneusi, Encephalitozoon spp. and Blastocystis spp. in Hair Goats in Türkiye

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Blastocystis spp., Enterocytozoon bieneusi and Encephalitozoon spp. are prevalent zoonotic gastrointestinal parasites that cause severe diarrhoea and enteric diseases in humans and animals worldwide. This study investigated the molecular occurrence, genetic diversity and zoonotic potential of E. bieneusi, Blastocystis spp.
Zuhal Önder, Sümmani Çifci, Batuhan Aşkım Arslanhan, Simge Şahin, Samba Deguene Diop, Alireza Sazmand, Önder Düzlü, Sadullah Uslu   +7 more
wiley   +1 more source

Sex differences in severity and mortality from COVID-19 : are males more vulnerable?

, 2020
Coronavirus disease 2019 (COVID-19) has shown high infection and mortality rates all over the world, and despite the global efforts, there is so far no specific therapy available for COVID-19.
Pradhan, Ajay,, Olsson, Per-Erik,
core   +1 more source

Clinical and genetic characteristics of a large international cohort of individuals with rare NR5A1/SF-1 variants of sex developmentResearch in context

EBioMedicine
Summary: Background: Steroidogenic factor 1 (SF-1/NR5A1) is essential for human sex development. Heterozygous NR5A1/SF-1 variants manifest with a broad range of phenotypes of differences of sex development (DSD), which remain unexplained.
Chrysanthi Kouri, Grit Sommer, Idoia Martinez de Lapiscina, Rawda Naamneh Elzenaty, Lloyd J.W. Tack, Martine Cools, S. Faisal Ahmed, Christa E. Flück, Saygin Abali, Zehra Yavas Abali, Leyla Akin, Maricruz Almaraz, Laura Audí, Murat Aydin, Antonio Balsamo, Federico Baronio, Jillian Bryce, Kanetee Busiah, Maria Caimari, Núria Camats-Tarruella, Ariadna Campos-Martorell, Luis Castaño, Anna Casteràs, Semra Çetinkaya, Yee-Ming Chan, Hedi L. Claahsen-van der Grinten, Ines Costa, Fatma Feyza Darendeliler, Justin H. Davies, Isabel Esteva, Helena Fabbri-Scallet, Courtney A. Finlayson, Emilio Garcia, Beatriz Garcia Cuartero, Alina German, Evgenia Globa, Gil Guerra-Junior, Julio Guerrero, Tulay Guran, Sabine E. Hannema, Olaf Hiort, Josephine Hirsch, Leuan Hughes, Marco Janner, Zofia Kolesinska, Katherine Lachlan, Anna Lauber-Biason, Jana Krenek Malikova, Dagmar l'Allemand, Nina Lenhnerr-Taube, Angela Lucas-Herald, Jamala Mammadova, Kenneth MсElreavey, Veronica Mericq, Isabel Mönig, Francisca Moreno, Julia Mührer, Marek Niedziela, Anna Nordenstrom, Burçe Orman, Sukran Poyrazoglu, Jose M. Rial, Meilan M. Rutter, Amaia Rodríguez, Tara Schafer-Kalkhoff, Kay-Sara Sauter, Sumudu Nimali Seneviratne, Maria Sredkova-Ruskova, Rieko Tadokoro-Cuccaro, Ajay Thankamony, Mónica Tomé, Amaia Vela, Malgorzata Wasniewska, David Zangen, Nataliya Zelinska   +74 more
doaj   +1 more source

Can Annotation‐Free Deep Learning Detect Periapical Bone Rarefactions on Panoramic Radiographs? A Paired Diagnostic Validation Study

International Journal of Imaging Systems and Technology, Volume 36, Issue 6, November 2026.
ABSTRACT This study aimed to compare an annotation‐free deep learning (DL) model with human evaluators for detecting periapical bone rarefactions (PBRs) on panoramic radiographs (PRs) and to assess the clinical acceptability of AI‐supported dental imaging.
José Evando da Silva‐Filho, Caio Marques Silva, Giovanna Tacchi, Igor Rodrigues‐Fontenele, Mateus Bôtto‐Marques, Sâmela Débora Mendes‐Dias, André Wescley Oliveira de Aguiar, Pedro Pedrosa Rebouças Filho, Paulo Leonardo Pontes Marques, Danielle Frota de Albuquerque, Eduardo Diogo Gurgel‐Filho   +10 more
wiley   +1 more source

Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines

Andrology, Volume 14, Issue 7, Page 1906-1928, October 2026.
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede, George Kanakis, Ewa Rajpert‐De Meyts, Davor Jezek, Ferran Algaba, Gert Dohle, Jolanta Slowikowska‐Hilczer, Sabine Kliesch, Hermann M. Behre, Csilla Krausz, Dimitrios G. Goulis, Niels Jørgensen   +11 more
wiley   +1 more source

Disorders/differences of sex development (DSDs) for primary care: the approach to the infant with ambiguous genitalia [PDF]

Translational Pediatrics, 2017
The initial management of the neonate with ambiguous genitalia can be a very stressful and anxious time for families, as well as for the general practitioner or neonatologist. A timely approach must be sensitive and attend to the psychosocial needs of the family.
openaire   +2 more sources