Results 71 to 80 of about 13,324 (296)

Generalized Nabla Differentiability and Integrability for Fuzzy Functions on Time Scales

open access: yesAxioms, 2020
This paper mainly deals with introducing and studying the properties of generalized nabla differentiability for fuzzy functions on time scales via Hukuhara difference.
R. Leelavathi   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Besov regularity for solutions of p-harmonic equations

open access: yesAdvances in Nonlinear Analysis, 2017
We establish the higher fractional differentiability of the solutions to nonlinear elliptic equations in divergence form, i.e., div⁡𝒜⁢(x,D⁢u)=div⁡F,{\operatorname{div}\mathcal{A}(x,Du)=\operatorname{div}F,} when 𝒜{\mathcal{A}} is a p-harmonic type ...
Clop Albert   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A Measure Zero UDS in the Heisenberg Group

open access: yesBruno Pini Mathematical Analysis Seminar, 2016
We show that the Heisenberg group contains a measure zero set N such that every real-valued Lipschitz function is Pansu differentiable at a point of N.
Andrea Pinamonti, Gareth Speight
doaj   +1 more source

Generalized Differentiability of Continuous Functions

open access: yesFractal and Fractional, 2020
Many physical phenomena give rise to mathematical models in terms of fractal, non-differentiable functions. The paper introduces a broad generalization of the derivative in terms of the maximal modulus of continuity of the primitive function.
Dimiter Prodanov
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Asymptotic Fr echet ´Differentiability

open access: yes, 2012
This chapter presents the current development of the first, unpublished proof of existence of points Fréchet differentiability of Lipschitz mappings to two-dimensional spaces.
Tiˇser Jaroslav   +2 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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