Results 71 to 80 of about 28,027 (297)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

A Measure Zero UDS in the Heisenberg Group

open access: yesBruno Pini Mathematical Analysis Seminar, 2016
We show that the Heisenberg group contains a measure zero set N such that every real-valued Lipschitz function is Pansu differentiable at a point of N.
Andrea Pinamonti, Gareth Speight
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

On some inequalities related to open Newton-Cotes formulas for differentiable convex functions with applications

open access: yesMiskolc Mathematical Notes
In this paper, first, we prove a novel integral identity involving a single time-differentiable function. Then, we prove some new inequalities associated with one of the open Newton-Cotes formulas for differentiable convex functions.
Ifra Bashir Sial   +3 more
doaj   +1 more source

Opial inequalities for a conformable ∆-fractional calculus on time scales [PDF]

open access: yesMathematica Moravica
In this paper, an Opial-type inequality is introduced on time scale for a conformal ∆-fractional differentiable function of order a, a ∈ (0, 1]. In the case where the certain weight functions are included, one generalization of the Opial inequality is ...
Mirković Tatjana, Bajić Tatjana
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Algebras of Differentiable Functions [PDF]

open access: yesProceedings of the American Mathematical Society, 1954
1. Let M be a compact differentiable manifold of class Cr, 1
openaire   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy