Results 101 to 110 of about 213,817 (308)

Comparison of Airborne Water Vapor Lidar Observations with ECMWF Analyses and first Assimilation Experiments

, 2006
Water vapor is the most important greenhouse gas and controls cloud formation and the evolution of weather systems. As its tropospheric concentration may rapidly vary over four orders of magnitude, accurate monitoring of water vapor, especially in the ...
Flentje, Harald, Kiemle, Christoph, Fix, Andreas, Dörnbrack, Andreas, Holm, Elias, Ehret, Gerhard, Weissmann, Martin   +6 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Intercomparison of Water Vapor Data Measured with Lidar during IHOP_2002. Part I: Airborne to Ground-Based Lidar Systems and Comparisons with Chilled-Mirror Hygrometer Radiosondes

, 2007
The water vapor data measured with airborne and ground-based lidar systems during the International H2O Project (IHOP_2002), which took place in the Southern Great Plains during 13 May–25 June 2002 were investigated.
Wulfmeyer, Volker, R. FERRARE, E. V. BROWELL, Ferrare, Richard, J. WANG, Ismail, Syed, S. KOOI, D. SUMMA, Schaberl, Thorsten, B. B. DEMOZ, Andreas Behrendt, Richard Ferrare, Whiteman, David N., T. SCHABERL, S. ISMAIL, DI GIROLAMO, Paolo, V. WUFMEYER, Demoz, Belay B., A. BEHRENDT, Kooi, Susan, Ehret, Gerhard, Summa, Donato, Demoz, Belay, Browell, Edward V., Kiemle, Christoph, Volker Wulfmeyer, Wang, Junhong, Behrendt, Andreas, Christoph Kiemle, Paolo Di Girolamo, D. N. WHITEMAN, Gerhard Ehret, Donato Summa, Syed Ismail, Belay B. Demoz, Bauer, Hans-Stefan, C. KIEMLE, Susan Kooi, H. S. BAUER, David N. Whiteman, Thorsten Schaberl, Junhong Wang, Browell, Edward, Girolamo, Paolo, G. EHRET, Edward V. Browell, Hans-Stefan Bauer, Whiteman, David   +47 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Research on Synchronous Inversion Algorithm Based on Tri-Wavelength DIAL

Optics
Traditionally, retrieving both temperature and CO2 concentration in atmospheric remote sensing has relied on two independent lidar systems, leading to increased system complexity and limited coordination.
Zhixiao Xu, Hangbo Hua, Jing Yu, Zhitian Niu, Ming Kong   +4 more
doaj   +1 more source

Latent Heat Fluxes over Complex Terrain from Airborne Water Vapour and Wind Lidars

, 2009
Tropospheric profiles of water vapour and wind were measured with a differential absorption lidar (DIAL) and a heterodyne detection Doppler wind lidar collo-cated onboard the DLR Falcon research aircraft in the past two years.
Kiemle, Christoph, Fix, Andreas, Rahm, Stephan, Wirth, Martin   +3 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Ongoing activities at LMD to prepare the CH4 space lidar mission MERLIN [PDF]

EPJ Web of Conferences
MERLIN (MEthane Remote LIdar missioN) is a space mission developed by France and Germany to monitor the atmospheric methane using an IPDA (Integrated Path Differential Absorption) lidar.
Gibert Fabien, Armante Raymond, Cassé Vincent, Chomette Olivier, Crevoisier Cyril, Delahaye Thibault, Edouart Dimitri, Nahan Frédéric, Tran Ha   +8 more
doaj   +1 more source

local differential absorption

Citation: 'local differential absorption' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14028 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests
openaire   +1 more source

Latent Heat Fluxes over Complex Terrain Measured by Airborne Water Vapour and Wind Lidars

, 2010
The combination of a water vapour and a wind lidar on an aircraft is an interesting new tool that allows to measure latent heat flux profiles and to portray the small- to mesoscale variability beneath the aircraft trajectory with high accuracy and ...
Kiemle, Christoph
core