Results 91 to 100 of about 330,789 (295)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Background: The Bacille Calmette-Guérin (BCG) vaccine against tuberculosis (TB) may have beneficial non-specific effects (NSEs) beyond the protection against TB. This may be related to modifications of the innate immune system. We investigated the effect
Nissen, Thomas Nørrelykke +8 more
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
White blood cell differential count in rabbits artificially infected with intestinal coccidia [PDF]
application/pdfThe aim of the present study was to examine the effect of intestinal coccidia upon the white cell count and differential leukocyte count of the infected rabbits. Two groups of rabbits were infected with various doses of intestinal coccidia
Aleksić-Bakrač, Nevenka +4 more
core
UMI-count modeling and differential expression analysis for single-cell RNA sequencing
Read counting and unique molecular identifier (UMI) counting are the principal gene expression quantification schemes used in single-cell RNA-sequencing (scRNA-seq) analysis.
Wenan Chen +5 more
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Aim:Idiopathic peripheral facial paralysis [Bell’s palsy (BP)] is the most common cause of acute, one-sided facial paralysis, whose etiopathogenesis is currently unknown. However, inflammation is considered to play a role in etiopathogenesis.
Hilal Susam Sen +5 more
doaj +1 more source
Total cell quantification in Cerebrospinal Fluid: Can Alinity hq be an effective alternative?
Introduction: Cell quantification in the cerebrospinal fluid (CSF) is a critical method for the diagnosis of subarachnoid bleeding, neuro-inflammatory and neoplastic pathologies.
Frederico Bragança +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source

