Results 251 to 260 of about 2,083,159 (309)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

MZF1 Inhibits TGFβ‐1/SMAD Signaling by Transcriptionally Activating SnoN to Augment Tumorigenic Potential in Colon Cancer

Advanced Science, EarlyView.
This study identifies MZF1 as a core regulator of colon cancer via SnoN‐mediated TGF‐β suppression, proposes 10Panx Acetate as a targeted inhibitor, and validates MZF1/SnoN as prognostic markers for aggressive disease. ABSTRACT Colon cancer progression is associated with transcriptional and signaling abnormalities.
Siqi Sheng, Mengxi Huang, Yiting Wang, Hongyu Wang, Haimei Feng, Xiaoming Bai, Jie Chen, Ke Xu, Xiaoyuan Chu, Zengjie Lei   +9 more
wiley   +1 more source

From Nash Equilibrium to Social Optimum and Back: A Mean Field Perspective. [PDF]

Appl Math Optim
Carmona R, Dayanıklı G, Delarue F, Laurière M.   +3 more
europepmc   +1 more source

A Metasynthesis on Perceptions of Sexism Among Video Game Players and the Video Game Industry. [PDF]

Behav Sci (Basel)
Denia Mondéjar J, Pérez-Martínez V, Vives-Cases C.   +2 more
europepmc   +1 more source

The Association Between Daily Screen Time and Childhood Overweight and Obesity: Current Evidence and Potential Mechanisms. [PDF]

Int J Gen Med
Lu L, Gu Y, Yang W, Liang Z.
europepmc   +1 more source

Evaluating the cognitive impact of exergames on community-dwelling older adults beyond laboratory settings: a systematic review and meta-analysis. [PDF]

Front Dement
Qian Y, Schwartz AM, Zhang Y, Kramer AF, Lopes AD, Chukoskie L.   +5 more
europepmc   +1 more source

Exploring the impact of specialist and generalist stars on organizational performance. [PDF]

PLoS One
Nalbantis G, Manger C, Pawlowski T, Yang P.   +3 more
europepmc   +1 more source

Community codes of conduct as proactive intervention for toxicity in games. [PDF]

Front Public Health
Kowert R.
europepmc   +1 more source

A Digital Behavioral Health Game for Adolescent Mental Health: A Prespecified Secondary Analysis of a Randomized Clinical Trial.

JAMA Netw Open
Barry CM, Boomer T, Haile K, Xie H, Fiellin LE.   +4 more
europepmc   +1 more source

Differential Hybrid Games [PDF]

ACM Transactions on Computational Logic, 2017
This article introducesdifferential hybrid games, which combine differential games with hybrid games. In both kinds of games, two players interact with continuous dynamics. The difference is that hybrid games also provide all the features of hybrid systems and discrete games, but only deterministic differential equations.
André Platzer
exaly   +4 more sources