Results 101 to 110 of about 234,443 (351)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Examination of differential item functioning in PISA through univariate and multivariate matching differential item functioning

International Journal of Assessment Tools in Education
The present research aims to examine whether the questions in the Program for the International Student Assessment (PISA) 2009 reading literacy instrument display differential item functioning (DIF) among the Turkish, French, and American samples based ...
Nizamettin Koç, Ahmet Yıldırım
doaj  

Psychometric properties of Generalized Anxiety Disorder-7 during COVID-19: item response theory analysis [PDF]

Psico-USF
This study evaluated the psychometric properties of the Generalized Anxiety Disorder Scale 7-item in a Brazilian sample during the COVID-19 pandemic using item response theory.
Beatriz Oliveira-Santos, Luanna dos Santos Silva, Dandara Palhano, André Faro   +3 more
doaj   +2 more sources

A meta-analysis of the Mantel-Haenszel procedure in the detection of DIF in dichotomous items [PDF]

, 2007
d de Murcia El objetivo del presente estudio consiste en describir el estado actualde la investigación sobre la eficacia del procedimiento Mantel-Haenszel(MH) como técnica de detección del Funcionamiento Diferencial del Ítem(Differential Item ...
Guilera, Georgina, Gómez Benito, Juana, Hidalgo Montesinos, Maria Dolores, Sánchez Meca, Julio   +3 more
core   +1 more source

Differential item functioning of the SON-R 2½-7[a] non-verbal intelligence test [PDF]

, 2012
A presença de uma quantidade considerável de itens com funcionamento diferencial (DIF) pode tornar um teste menos válido. Assim, este estudo investigou a existência de DIF no teste de inteligência SON-R 2½-7[a]. O teste é a versão abreviada do SON-R 2½-7,
Jesus, Girlene Ribeiro de, Karino, Camila Akemi, Laros, Jacob Arie   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Exploring differential item functioning in the SF-36 by demographic, clinical, psychological and social factors in an osteoarthritis population [PDF]

, 2013
The SF-36 is a very commonly used generic measure of health outcome in osteoarthritis (OA). An important, but frequently overlooked, aspect of validating health outcome measures is to establish if items work in the same way across subgroup of a ...
A Williams, AJ Dallmeijer, AJ Perkins, B Pollard, BD Zumbo, BD Zumbo, Beth Pollard, C Bombardier, C Lewis, CA McHorney, Diane Dixon, DJ Cooke, F Wolfe, H Swaminathan, J Eachus, JA Teresi, JA Teresi, JA Teresi, JB Bjorner, JB Bjorner, JE Ware, JH Kellgren, M Reckase, Marie Johnston, N Bellamy, NW Scott, OPCS, P Juni, PB Baltes, PK Crane, RO Anderson, SP McKenna, T Covic, WF Velicer, WJ Taylor   +34 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Investigating the Impact of Item Parameter Drift for Item Response Theory Models with Mixture Distributions

Frontiers in Psychology, 2016
This study investigates the impact of item parameter drift (IPD) on parameter and ability estimation when the underlying measurement model fits a mixture distribution, thereby violating the item invariance property of unidimensional item response theory (
Yoon Soo ePark, Young-Sun eLee, Kuan eXing   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source