Results 101 to 110 of about 48,174 (313)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Exploring differential item functioning in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

open access: yesBMC Musculoskeletal Disorders, 2012
Background The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a widely used patient reported outcome in osteoarthritis. An important, but frequently overlooked, aspect of validating health outcome measures is to establish if ...
Pollard Beth   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Use of differential item functioning (DIF) analysis for bias analysis in test construction

open access: yesSA Journal of Industrial Psychology, 2004
When differential item functioning (DIF) item analysis procedures based on item response theory (IRT) are used during test construction, it is possible to draw item characteristic curves for the same item for different subgroups.
Marié De Beer
doaj   +1 more source

Differential item functioning potensi akademik pada kelompok SMA–MA [PDF]

open access: yes, 2013
Evidence of fairness indicated by item equality functioning between groups compared. Items unfairness showed by differential item functioning (DIF). This study aimed at identify items of Potensi Akademik (PA) Seleksi Penerimaan Mahasiswa Baru – Perguruan
Ridho, Ali
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Avaliação de desempenho logístico no serviço ao cliente baseada na teoria da resposta ao item [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Produção, Florianópolis, 2011A busca por alternativas para avaliar o desempenho logístico foi o que instigou esta pesquisa.
Vey, Ivan Henrique
core  

Differential item functioning by gender for Item 46 (Staff are helpful, kind and polite).

open access: yes, 2016
Differential item functioning by gender for Item 46 (Staff are helpful, kind and polite).
Patrick Callaghan (2558638)   +4 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Gender differential item functioning on a national field-specific test: The case of PhD entrance exam of TEFL in Iran [PDF]

open access: yesIranian Journal of Language Teaching Research, 2016
Differential Item Functioning (DIF) exists when examinees of equal ability from different groups have different probabilities of successful performance in a certain item.
Alireza Ahmadi, Ali Darabi Bazvand
doaj  

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