Results 101 to 110 of about 48,174 (313)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Background The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a widely used patient reported outcome in osteoarthritis. An important, but frequently overlooked, aspect of validating health outcome measures is to establish if ...
Pollard Beth +2 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Use of differential item functioning (DIF) analysis for bias analysis in test construction
When differential item functioning (DIF) item analysis procedures based on item response theory (IRT) are used during test construction, it is possible to draw item characteristic curves for the same item for different subgroups.
Marié De Beer
doaj +1 more source
Differential item functioning potensi akademik pada kelompok SMA–MA [PDF]
Evidence of fairness indicated by item equality functioning between groups compared. Items unfairness showed by differential item functioning (DIF). This study aimed at identify items of Potensi Akademik (PA) Seleksi Penerimaan Mahasiswa Baru – Perguruan
Ridho, Ali
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Avaliação de desempenho logístico no serviço ao cliente baseada na teoria da resposta ao item [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Produção, Florianópolis, 2011A busca por alternativas para avaliar o desempenho logístico foi o que instigou esta pesquisa.
Vey, Ivan Henrique
core
Differential item functioning by gender for Item 46 (Staff are helpful, kind and polite).
Differential item functioning by gender for Item 46 (Staff are helpful, kind and polite).
Patrick Callaghan (2558638) +4 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Gender differential item functioning on a national field-specific test: The case of PhD entrance exam of TEFL in Iran [PDF]
Differential Item Functioning (DIF) exists when examinees of equal ability from different groups have different probabilities of successful performance in a certain item.
Alireza Ahmadi, Ali Darabi Bazvand
doaj

