Results 61 to 70 of about 670,280 (308)
BioMed Research International, 2015 Mechanical unloading by left ventricular assist devices (LVADs) in advanced heart failure (HF), in addition to improving symptoms and end-organ perfusion, is supposed to stimulate cellular and molecular responses which can reverse maladaptive cardiac ...
C. Barsanti +10 more
semanticscholar +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
, 2010 In this paper a novel device aimed at controlling the mechanical vibrations of plates by means of a set of electrically-interconnected piezoelectric actuators is described. The actuators are embedded uniformly in the plate wherein they connect every node
Batra +17 more
core +1 more source
Control of the weakly damped System with the embedded system support [PDF]
, 2018 This paper deals with the experimental verification of the importance of embedded systems with an applied MEMS sensor in controlling weakly damped systems. The aim is to suppress actively residual oscillations.
Kondelová, Anna +2 more
core +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
physica status solidi (RRL) – Rapid Research LettersMembranotronic devices are artificial neural membranes mimicing the functionality of biological neural networks. These devices rely on the emergence of negative differential resistance (NDR). A minimalistic physical model for membranotronic devices capable of generating NDR is presented.
Max Huber +4 more
openaire +1 more source
Probing the charge of a quantum dot with a nanomechanical resonator
, 2012 We have used the mechanical motion of a carbon nanotube (CNT) as a probe of the average charge on a quantum dot. Variations of the resonance frequency and the quality factor are determined by the change in average charge on the quantum dot during a ...
A. Taspinar +8 more
core +2 more sources
Limit cycle behavior of smart fluid dampers under closed loop control [PDF]
, 2005 Semiactive vibration dampers offer an attractive compromise between the simplicity and fail safety of passive devices, and the weight, cost, and complexity of fully active systems.
Sims, N.D.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Analysis of main dynamic parameters of split power transmission [PDF]
Transport, 2008 The review carried out had shown one basic approach of split power transmission to the organization of drive which is applied to stepless transmissions of tractors and parallel hybrid cars.
A. Janulevičius, K. Giedra
doaj +2 more sources