Results 71 to 80 of about 313,156 (264)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Jixie chuandong, 2006 Tilting device of converter is the most important mechanical equipment on steel-making. A new type multipoint engagement full suspension flexible gearing is introduced. Primal reducer adopts planet differential load balancing mechanism which can make the
张玉忠, 王铁
doaj
Behaviour study of an eccentric pulley transmission system using systemic methods
Dyna, 2019 This paper describes a case study carried out on the behaviour of an eccentric pulley transmission system housed in a manually operated abdominal-intestinal assistant device for human use.
Iñaki Esnal Angulo +1 more
doaj +1 more source
IEEE Access, 2023 An emerging differential dynamic microscopy technique has been successfully used for quantitative dynamic investigation of micro-particle suspension, leading to a rheological assessment of the solution.
Ungkarn Jarujareet +3 more
doaj +1 more source
Probing the charge of a quantum dot with a nanomechanical resonator
, 2012 We have used the mechanical motion of a carbon nanotube (CNT) as a probe of the average charge on a quantum dot. Variations of the resonance frequency and the quality factor are determined by the change in average charge on the quantum dot during a ...
A. Taspinar +8 more
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Limit cycle behavior of smart fluid dampers under closed loop control [PDF]
, 2005 Semiactive vibration dampers offer an attractive compromise between the simplicity and fail safety of passive devices, and the weight, cost, and complexity of fully active systems.
Sims, N.D.
core +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
FEBS Open Bio, EarlyView.This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang +6 more
wiley +1 more source
Low Power Resonant Optical Excitation of an Optomechanical Cavity
, 2010 We demonstrate the actuation of a double beam opto-mechanical cavity with a sinusoidally varying optical input power. We observe the driven mechanical motion with only 200 nW coupled to the optical cavity mode.
Altug +23 more
core +1 more source
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source