Results 81 to 90 of about 3,187,807 (353)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Caratheodory operator of differential forms

open access: yesJournal of Inequalities and Applications, 2011
This article is devoted to extensions of some existing results about the Caratheodory operator from the function sense to the differential form situation.
Tang Zhaoyang, Zhu Jianmin
doaj  

Effective descent for differential operators

open access: yesJournal of Algebra, 2010
A theorem of N. Katz \cite{Ka} p.45, states that an irreducible differential operator $L$ over a suitable differential field $k$, which has an isotypical decomposition over the algebraic closure of $k$, is a tensor product $L=M\otimes_k N$ of an absolutely irreducible operator $M$ over $k$ and an irreducible operator $N$ over $k$ having a finite ...
Compoint, Elie   +2 more
openaire   +6 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Power operations and differentiations associated with supersymmetric polynomials on a Banach space

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2020
We consider different approaches to constructing power operations on the ring of multisets associated with supersymmetric polynomials of infinitely many variables. Some relations between constructed power operations are established.
I.V. Chernega   +2 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

On the isospectral beams

open access: yesElectronic Journal of Differential Equations, 2005
The free undamped infinitesimal transverse vibrations of a thin straight beam are modelled by a forth-order differential equation. This paper investigates the families of fourth-order systems which have one spectrum in common, and correspond to four ...
Kazem Ghanbari
doaj  

On Certain Analogues of Noor Integral Operators Associated with Fractional Integrals

open access: yesJournal of Function Spaces
In this paper, we employ a q-Noor integral operator to perform a q-analogue of certain fractional integral operator defined on an open unit disc. Then, we make use of the Hadamard convolution product to discuss several related results.
Mojtaba Fardi   +2 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

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