Results 91 to 100 of about 2,938,585 (308)

Technology diffusion in a differentiated industry [PDF]

, 1994
This paper investigates the adoption timing pattern of a cost-reducing innovation in a differentiated oligopolistic industry. It compares price and quantity market competition with the second-best optimal adoption rule.
Petrakis, Emmanuel
core   +1 more source

Elementary Teachers’ Acceptance of Digital Learning Platforms for Differentiated and Deep Learning: An Empirical Study Based on the UTAUT Framework

International Journal of Education and Teaching Zone
The effective integration of digital technology in differentiated and deep learning requires a clear understanding of the factors influencing teachers’ acceptance of instructional platforms.
Iis Hartati, Yunus Abidin, Dede Trie Kurniawan   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The effect of rater training on rating behaviors in peer assessment among secondary school students

International Journal of Assessment Tools in Education
This study aimed to measure the effect of rater training given to improve the peer assessment skills of secondary school students on rater behaviors using the many-facet Rasch Measurement model.
Naizra Tursynbayeva, Umur Öç, İsmail Karakaya   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

No evidence of disease activity (NEDA) in multiple sclerosis - Shifting the goal posts

Annals of Indian Academy of Neurology, 2019
A combined endpoint measure to define no evidence of disease activity (NEDA) is becoming increasingly appealing in the treatment of multiple sclerosis (MS). Initial efforts using a 3 parameter NEDA monitored disease activity using clinical and MRI lesion
Lekha Pandit
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Modelowe badania wpływu zagęszczenia gleby na gospodarkę wodną warstwy uprawnej

Agronomy Science, 2004
The studies aimed at determining to what degree differentiated soil compaction can influence the process of evaporation from the soil surface and the moisture content in particular layers of the soil profile.
Stanisław Włodek, Andrzej Biskupski, Jan Pabin   +2 more
doaj  

Classification of iPSC-derived cultures using convolutional neural networks to identify single differentiated neurons for isolation or measurement

Discover Artificial Intelligence
Understanding neurodegenerative disease pathology requires a close examination of neurons and their processes. However, image-based single-cell analyses of neurons often require laborious and time-consuming manual classification tasks. Here, we present a
Purva Patel, Lina K. Mohammed Ali, Uma Kaushik, Mallory Wright, Kaylee Green, Jason E. Waligorski, Colin L. Kremitzki, Graham W. Bachman, Serena N. Elia, William J. Buchser   +9 more
doaj   +1 more source