Molecular Pathogenesis and Targeted Therapies in Well-Differentiated Thyroid Carcinoma [PDF]
Four proto-oncogenes commonly associated with well-differentiated thyroid carcinoma, rearranged during transfection (RET)/papillary thyroid cancer, BRAF, RAS, and PAX8/peroxisome proliferator activated receptor-γ, may carry diagnostic and prognostic ...
Jung Guk Kim
doaj +1 more source
Actions of Thyroid Hormones on Thyroid Cancers
L-Thyroxine (T4) is the principal ligand of the thyroid hormone analogue receptor on the extracellular domain of integrin αvβ3. The integrin is overexpressed and activated in cancer cells, rapidly dividing endothelial cells, and platelets.
Shaker A. Mousa +8 more
doaj +1 more source
The dedifferentiation of differentiated thyroid cancer (DTC) is a challenging problem for radioactive iodine (131I) treatment, also known as radioiodine refractory differentiated thyroid cancer (RAIR-DTC). The purpose of this study was to further explore
Shasha Hou +7 more
doaj +1 more source
Russian clinical practice guidelines for diagnosis and treatment of differentiated thyroid cancer
The project of Russian clinical practice guidelines for diagnosis and treatment of differentiated thyroid cancer is dedicated to the management of patients with differentiated thyroid cancer. The guideline modifications 2016 include the following matters:
Dmitriy Germanovich Bel'tsevich +5 more
doaj +1 more source
2017 Russian clinical practice guidelines for differentiated thyroid cancer diagnosis and treatment
The Russian clinical practice guidelines for diagnosis and treatment of differentiated thyroid cancer is dedicated to the management of patients with differentiated thyroid cancer.
Dmitriy G. Beltsevich +14 more
doaj +1 more source
BackgroundThe incidence rate of children with thyroid cancer has an increasing trend. This study aimed to investigate the clinical characteristics and therapeutic approaches of differentiated thyroid cancer (DTC) in Chinese children.Materials and ...
Chun Chen +21 more
doaj +1 more source
Prognostic value of somatic mutation testing and different methods of treatment of low-risk differentiated thyroid cancer [PDF]
Background: Using molecular testing for prediction the course of the disease could possibly help doctors in making therapeutic decisions about the management of patients, because it remains controversial issues in low-risk differentiated thyroid cancer ...
Vera A. Kachko +2 more
doaj +1 more source
Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers [PDF]
Anaplastic thyroid cancer (ATC) is a lethal human cancer with a 5-year survival rate of less than 10%. Recently, its genomic and transcriptomic characteristics have been extensively elucidated over 5 years owing to advance in high throughput sequencing ...
Seong-Keun Yoo +3 more
doaj +1 more source
Unusual metastases from differentiated thyroid cancers: A multicenter study in Korea.
BackgroundAlthough infrequent, distant metastasis from differentiated thyroid cancer is the main cause of mortality in patients and mostly involves the lung, bone, and brain. Distant metastases to other sites in differentiated thyroid cancer patients are
Jee Hee Yoon +9 more
doaj +1 more source
The Role of Genetic Polymorphisms in Differentiated Thyroid Cancer: A 2023 Update
Thyroid cancer is the most common endocrine malignancy, with an increasing trend in the past decades. It has a variety of different histological subtypes, the most frequent one being differentiated thyroid cancer, which refers to papillary carcinoma, the
Robert Aurelian Tiucă +2 more
doaj +1 more source

