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Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers [PDF]

Endocrinology and Metabolism, 2020
Anaplastic thyroid cancer (ATC) is a lethal human cancer with a 5-year survival rate of less than 10%. Recently, its genomic and transcriptomic characteristics have been extensively elucidated over 5 years owing to advance in high throughput sequencing ...
Seong-Keun Yoo, Young Shin Song, Young Joo Park, Jeong-Sun Seo   +3 more
doaj   +1 more source

Tyrosine kinase inhibitors for the therapy of anaplastic thyroid cancer [PDF]

, 2015
Anaplastic thyroid cancer (ATC) is often incurable so new therapeutic approaches are needed. Tyrosine kinases inhibitors (such as imanitib, sunitinib or sorafenib) are under evaluation for the treatment of ATC.
Bond JA, Cohen EE, Dowlati A, Goulart B, Grande E, Hayashi N, Ibrahim N, Klopper JP, Mahlknecht U, Ohta K, Ruggeri RM, Sherman SI   +11 more
core   +1 more source

Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) may be superior to C-reactive protein (CRP) for predicting the occurrence of differentiated thyroid cancer

Endocrine Regulations, 2017
Objectives. NLR (neutrophil-lymphocyte ratio) and PLR (platelet-lymphocyte ratio) are prognostic markers of differentiated thyroid cancers. In our study, we evaluated NLR, PLR and C-reactive protein (CRP) for predicting the occurence of differentiated ...
Ozmen S, Timur O, Calik I, Altinkaynak K, Simsek E, Gozcu H, Arslan A, Carlioglu A   +7 more
doaj   +1 more source

Well-differentiated thyroid cancer disclosed during pregnancy. Management experience

Эндокринная хирургия, 2015
Thyroid cancer have the second place as malignancy detectable during pregnancy. Disclose of thyroid cancer during pregnancy raises many questions among endocrinologists, oncologists and obstetricians.
A. A. Ilyin, P. O. Rumyantsev, D. N. Derbugov, D. N. Semin, N. V. Severskaya, P. A. Isaev, S. V. Vasilkov, V. S. Medvedev, V. V. Polkin   +8 more
doaj   +1 more source

Study of Serum Leptin in Well-differentiated Thyroid Carcinoma: Correlation with Patient and Tumor Characteristics [PDF]

, 2014
Background There is a proven relationship between obesity and several cancers including breast, endometrium, colorectal, and esophagus. With the increasing incidence of both obesity and thyroid cancer, we designed the present study to investigate a ...
Abdel-Aziz, TE, Elwafa, RA, Elwafa, WA, Rehem, RA   +3 more
core   +1 more source

Significance of telomerase reverse-transcriptase promoter mutations in differentiated thyroid cancer

Formosan Journal of Surgery, 2021
Background: Telomerase reverse-transcriptase (TERT) encodes the reverse transcriptase of telomerase, and TERT promoter mutations are enriched in advanced thyroid cancer.
Hung-Fei Lai, Chi-Yu Kuo, Shih-Ping Cheng   +2 more
doaj   +1 more source

Prophylactic central lymph node dissection in differentiated thyroid cancer – benefits and risk [PDF]

Folia Medica, 2022
Introduction: Papillary thyroid cancer is the most common thyroid malignancy. Lymph nodes involvement is common in differentiated thyroid cancer, and cervical lymph node micrometastases are observed in up to 85% of patients with papillary thyroid cancer ...
Gancho G. Kostov, Rossen S. Dimov, Mladen I. Doykov   +2 more
doaj   +3 more sources

Risk stratification of neck lesions detected sonographically during the follow-up of differentiated thyroid cancer [PDF]

, 2016
Context: The European Thyroid Association (ETA) has classified post-treatment cervical ultrasound findings in thyroid cancer patients based on their association with disease persistence/recurrence.
BIFFONI, Marco, Costante, Giuseppe, DURANTE, COSIMO, FILETTI, SEBASTIANO, GIACOMELLI, Laura, GRANI, Giorgio, LAMARTINA, LIVIA, LUPO, STEFANIA, MARANGHI, MARIANNA, plasmati, katia, SPONZIELLO, Marialuisa, TRULLI, FABIANA, VERRIENTI, Antonella   +12 more
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The Role of Genetic Polymorphisms in Differentiated Thyroid Cancer: A 2023 Update

Biomedicines, 2023
Thyroid cancer is the most common endocrine malignancy, with an increasing trend in the past decades. It has a variety of different histological subtypes, the most frequent one being differentiated thyroid cancer, which refers to papillary carcinoma, the
Robert Aurelian Tiucă, Oana Mirela Tiucă, Ionela Maria Pașcanu   +2 more
doaj   +1 more source

A novel risk stratification model based on tumor size and multifocality to predict recurrence in pediatric PTC: comparison with adult PTC

Frontiers in Endocrinology
BackgroundPediatric papillary thyroid cancer presents with a more advanced stage of disease than adult PTC; and it is more likely to be aggresive and distant metastases, although the survival rate is high.MethodsA retrospective observational study was ...
Rui Du, Ying Zhang, Jiedong Kou, Jingting Li, Chengqiu Sui, Daqi Zhang, Yantao Fu, Le Zhou, Qingfeng Fu, Fang Li, Gianlorenzo Dionigi, Gianlorenzo Dionigi, Nan Liang, Hui Sun   +13 more
doaj   +1 more source