Results 71 to 80 of about 59,250 (306)

Management of Differentiated Thyroid Cancer in Pregnancy [PDF]

Journal of Thyroid Research, 2011
In young women, differentiated thyroid cancer is the second most common malignancy diagnosed around the time of pregnancy. Management of thyroid cancer during pregnancy poses distinct challenges due to concerns regarding maternal and fetal well-being.
Imran, Syed Ali, Rajaraman, Murali
openaire   +2 more sources

Differentiated Thyroid Cancer: A Health Economic Review

, 2021
The incidence of differentiated thyroid cancer (DTC) is rising, mainly because of an increased detection of asymptomatic thyroid nodularity revealed by the liberal use of thyroid ultrasound.
Klaas Van Den Heede, Neil S. Tolley, Fausto F. Palazzo, Aimee N. Di Marco   +3 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Fine needle biopsy in differential diagnosis of nodular goiter with autoimmune thyroiditis and differentiated thyroid cancers

Journal of Education, Health and Sport, 2017
We examined 75 women with nodular NGAIT and 12 patients with differentiated thyroid cancer during 2015-2016. We have carried out an immunohistochemical study by means of monoclonal antibodies against Fas, FasL, Bcl-2, P53 and Ki67 antigens using the ...
M. I. Sheremet, L. P. Sydorchuk, V. O. Shidlovskyi, A. D. Bedenyuk, A. I. Popovych, O. V. Lazaruk   +5 more
doaj   +3 more sources

Salidroside inhibits migration and invasion of poorly differentiated thyroid cancer cells

Thoracic Cancer, 2019
Background No effective treatment is currently available for poorly differentiated thyroid cancer which is resistant to radioiodine, especially with migration and invasion. A great number of researches have revealed the anticancer effects of salidroside,
Hongxia Shang, Shengnan Wang, Jinming Yao, Congcong Guo, Jianjun Dong, Lin Liao   +5 more
doaj   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

A study of the role of DIO1 and DIO2 polymorphism in thyroid cancer and drug response to therapy in the Saudi population

Saudi Pharmaceutical Journal, 2019
Background: Deiodinases comprise a group of selenoproteins that regulate the bioavailability of active thyroid hormones (TH) in a time and tissue specific fashion.
Maha M. AlRasheed, Ashwaq AlAnzi, Rawan AlShalhoub, Norah Abanmy, Dana Bakheet   +4 more
doaj   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source

Update on epidemiology classification, and management of thyroid cancer [PDF]

Libyan Journal of Medicine, 2006
Thyroid cancer represents approximately 0.5–1% of all human malignancy1. In the UK the incidence of thyroid cancer is 2-3 per 100,000 populations 2. In geographical areas of low iodine intake and in areas exposed to nuclear disasters the incidence of ...
Heitham Gheriani
doaj