Results 81 to 90 of about 4,224,202 (187)
Fréchet differentiability via partial Fréchet differentiability
Commentationes Mathematicae Universitatis CarolinaeLet $X_1, \dots, X_n$ be Banach spaces and $f$ a real function on $X=X_1 \times\dots \times X_n$. Let $A_f$ be the set of all points $x \in X$ at which $f$ is partially Fr\' echet differentiable but is not Fr\' echet differentiable. Our results imply that if $X_1, \dots, X_{n-1}$ are Asplund spaces and $f$ is continuous (resp.
openaire +3 more sources
Quadratic Poisson brackets and Drinfel'd theory for associative algebras
, 1995 Quadratic Poisson brackets on associative algebras are studied. Such a bracket compatible with the multiplication is related to a differentiation in tensor square of the underlying algebra.
A. A. Balinsky +8 more
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Xbra modulates the activity of linker region phosphorylated Smad1 during Xenopus development
Scientific ReportsThe Bmp/Smad1 pathway plays a crucial role in developmental processes and tissue homeostasis. Mitogen-activated protein kinase (Mapk)/Erk mediated phosphorylation of Smad1 in the linker region leads to Smad1 degradation, cytoplasmic retention and ...
Santosh Kumar +6 more
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Multi‐layered stochasticity and paracrine signal propagation shape the type‐I interferon response
Molecular Systems Biology, 2012 The cellular recognition of viruses evokes the secretion of type‐I interferons (IFNs) that induce an antiviral protective state. By live‐cell imaging, we show that key steps of virus‐induced signal transduction, IFN‐β expression, and induction of IFN ...
Ulfert Rand +10 more
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Channel Management and differentiation strategies: A case study from the market for fresh produce [PDF]
The paper analyses the current differentiation strategies in the market for fresh produce. First a short review of the literature on channel structure and product differentiation is presented, in order to identify, on a theoretical grounding the ...
Hingley, Martin, Sodano, Valeria
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Expression of neurogenin3 reveals an islet cell precursor population in the pancreas [PDF]
, 2000 Differentiation of early gut endoderm cells into the endocrine cells forming the pancreatic islets of Langerhans depends on a cascade of gene activation events controlled by transcription factors including the basic helix-loop-helix (bHLH) proteins.
Anderson, David J. +8 more
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Costly horizontal differentiation [PDF]
We study the effect of quadratic differentiation costs in the Hotelling model of endogenous product differentiation. The equilibrium location choices are found to depend on the magnitude of the differentiation costs (relatively to the transportation ...
Joana Pinho, João Correia-da-Silva
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Ehbp1 orchestrates orderly sorting of Wnt/Wingless to the basolateral and apical cell membranes
EMBO ReportsWingless (Wg)/Wnt signaling plays a critical role in both development and adult tissue homeostasis. In the Drosophila larval wing disc epithelium, the orderly delivery of Wg/Wnt to the apical and basal cell surfaces is essential for wing development ...
Yuan Gao +7 more
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Role of the Mitochondrial Genome During Early Development in Mice [PDF]
, 1973 The role of the mitochondrial genome in early development and differentiation was studied in mouse embryos cultured in vitro from the two to four cell stage to the blastocyst (about 100 cells).
Chase, David G., Pikó, Lajos
core
eLifeAging increases the risk of a myriad of chronic diseases, which are expensive and difficult to treat owing to their various risk factors. Repurposing existing medications has accelerated the development of therapies aimed at slowing aging. In this study,
Wencong Lyu +10 more
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