Experimental Cardiac Fibrosis: Differential Time Course of Responses to Mineralocorticoid-Salt Administration [PDF]
The rapid (1-4 h) responses of epithelial target tissues to mineralocorticoids contrast with the days/weeks apparently required for responses in the cardiovascular system. The present study explores the time course and pattern of early events leading to cardiac fibrosis in the mineralocorticoid-salt rat model.
G, Fujisawa +3 more
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Attenuation of Response to Repeated Drug Administration: A Proposal for Differentiating Tachyphylaxis and Tolerance [PDF]
Attenuation of drug response with repeated administration is referred to as tachyphylaxis or tolerance, though the distinction between these two is obscured through both their usage in the literature and imprecise definitions in common pharmacology texts.
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IntroductionLung transplantation often results in primary and/or chronic dysfunctions that are related to early perioperative innate allo-responses where myeloid subsets play a major role. Corticosteroids are administered upon surgery as a standard-of-care but their action on the different myeloid cell subsets in that context is not known.MethodsTo ...
Matthieu Glorion +20 more
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Differential peptidomics assessment of strain and age differences in mice in response to acute cocaine administration [PDF]
AbstractNeurochemical differences in the hypothalamic‐pituitary axis between individuals and between ages may contribute to differential susceptibility to cocaine abuse. This study measured peptide levels in the pituitary gland (Pit) and lateral hypothalamus (LH) in adolescent (age 30 days) and adult (age 65 days) mice from four standard inbred strains,
Elena V, Romanova +6 more
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On the Issue of Split of State and Municipal Procurement
The current legislation of the Russian Federation in the field of procurement for state and municipal needs is not perfect and has a number of gaps. The article deals with the problem of differentiation of illegal behavior of customers from justified in ...
S. M. Rukavishnikov
doaj +1 more source
Managing temporary workers in higher education: still at the margin? [PDF]
Purpose – To evaluate whether “numerical flexibility” – specifically a form of temporary and precarious employment – hourly-paid part-time teaching in the UK higher education sector – adds strategic value and demonstrates good practice.
Colin Bryson +2 more
core +1 more source
The article is devoted to the implementation of Russian Federation region's legislation on administrative offences on the municipal level. Based on the principle of differentiation of federal and region jurisdiction and being under the joint jurisdiction
Inna G. Mityunova / Инна Г. Митюнова
doaj +1 more source
A study of subsidiaries views of information systems strategic planning in multinational organisations [PDF]
This research examines information systems strategic planning (ISSP) in multinationals from the perspective of the subsidiaries. The research was carried out through interviews with the IT and business managers in subsidiaries of nine large American ...
Mohdzaher, Mohdzain, Ward, John
core +1 more source
Differential response of Iberian and lean pig crossbreeds to dietary linoleic acid administration
We aimed to determine whether the response of linoleic acid (C18:2 n-6) tissue concentration to dietary C18:2 n-6 administration, in the finishing period, is done in a different way in Iberian pig compared with a lean genotype. Therefore, 48 pigs, 24 of a lean genotype (Large White × Great York) and 24 of a fat genotype (Iberian × Duroc) were offered ...
Isabel, Beatriz +4 more
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Differential Symptom Reporting by Mode of Administration of the Assessment [PDF]
Automated voice response (AVR) systems have been used to collect patient-reported outcome data. Mode of administration of the assessment may affect patient reporting.To evaluate if there is a differential reporting of symptoms by the mode of assessment: AVR versus a live telephone interview among cancer patients with solid tumors undergoing ...
Alla, Sikorskii +4 more
openaire +2 more sources

