Results 31 to 40 of about 9,718 (234)

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen, Ronald D. Barr, Erin Strumpf, Mariam El‐Zein, Eduardo L. Franco, Talía Malagón   +5 more
wiley   +1 more source

Legal Classification of Non-Donation CSR Funds in Village Financial Governance

Jurnal USM Law Review
This study examines the legal ambiguity surrounding the integration of non-donation Corporate Social Responsibility (CSR) funds into village financial governance in Indonesia, particularly regarding the uncertain boundary between private corporate ...
Eldy Satria Noerdin, Amir Minabari, Alvin Evrialdo Noerdin   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Problems of legal regulation of disciplinary liability of state civil servants: from principles to the system of penalties

Russian Studies in Law and Politics
Background. The article discusses the problems of implementing disciplinary responsibility of civil servants (hereinafter referred to as civil servants).
Anton G. Monetov
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Joint Data Responsibility in Global Digital Trade: A Meso-Level Comparative Analysis of the European Union, the United States, and China

SAGE Open
Digital trade exposes increasing tensions between cross-border data flows, personal data protection, and national security. Existing scholarship has largely addressed these issues either at the macro level, through debates on data sovereignty, or at the ...
Yifan Guo
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Differential response of Iberian and lean pig crossbreeds to dietary linoleic acid administration

Spanish Journal of Agricultural Research, 2014
We aimed to determine whether the response of linoleic acid (C18:2 n-6) tissue concentration to dietary C18:2 n-6 administration, in the finishing period, is done in a different way in Iberian pig compared with a lean genotype. Therefore, 48 pigs, 24 of a lean genotype (Large White × Great York) and 24 of a fat genotype (Iberian × Duroc) were offered ...
Isabel, Beatriz, Cordero, Gustavo, Olivares, Alvaro, Daza, Argimiro, Lopez-Bote, Clemente J.   +4 more
openaire   +5 more sources

BOLD and Perfusion Response to Finger-Thumb Apposition after Acetazolamide Administration: Differential Relationship to Global Perfusion [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2003
The authors studied the effects of altering global cerebral blood flow on both blood oxygen level–dependent (BOLD) response and perfusion response to finger-thumb apposition. A PICORE/QUIPSS II protocol was used to collect interleaved BOLD-weighted and perfusion-weighted images on eight finger-thumb apposition trials.
Gregory G, Brown, Lisa T, Eyler Zorrilla, Bassem, Georgy, Sandra S, Kindermann, Eric C, Wong, Richard B, Buxton   +5 more
openaire   +2 more sources