Results 241 to 250 of about 10,005 (276)
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The Differential Response of Tissue Catalase Activity to Chronic Alcohol Administration in the Rat
Alcoholism: Clinical and Experimental Research, 1981Sprague‐Dawley male rats maintained on the Lieber/ DeCarli liquid alcohol diet for 40 days showed an increase in heart, decrease in liver, and no change in erythrocyte or skeletal muscle catalase levels when compared to pair‐fed controls.
E G, DeMaster, E, Kaplan, E, Chesler
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Pharmacology Biochemistry and Behavior, 1986
Rats were pretreated with saline or with behaviorally equivalent doses of clozapine (10.0 mg/kg) or haloperidol (1.0 mg/kg) twice daily for six consecutive days. On the following day, amygdaloid neurons in clozapine-pretreated rats responded to a challenge injection of this drug with a significantly greater increase in firing rate than saline controls.
G D, Anderson, G V, Rebec
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Rats were pretreated with saline or with behaviorally equivalent doses of clozapine (10.0 mg/kg) or haloperidol (1.0 mg/kg) twice daily for six consecutive days. On the following day, amygdaloid neurons in clozapine-pretreated rats responded to a challenge injection of this drug with a significantly greater increase in firing rate than saline controls.
G D, Anderson, G V, Rebec
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Differential response of calmodulin genes in the mouse brain after systemic kainate administration
Neuroscience, 1997In the central nervous system, many of the effects resulting from an increase in the intracellular levels of calcium are mediated by calmodulin, a major calcium-binding protein in the mammalian brain. Calmodulin is expressed by three different genes, namely CaM I, CaM II and CaM III, all of which encode an identical protein.
Solà, Carme +2 more
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Journal of Psychiatric Research, 2000
In a preliminary study, we performed the combined dexamethasone/CRH test on patients with major depressive and dysthymic disorders as well as healthy controls. The ACTH response was significantly enhanced in the major depression group compared to the control group and tended to be heightened compared to the dysthymia group.
A, Oshima +7 more
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In a preliminary study, we performed the combined dexamethasone/CRH test on patients with major depressive and dysthymic disorders as well as healthy controls. The ACTH response was significantly enhanced in the major depression group compared to the control group and tended to be heightened compared to the dysthymia group.
A, Oshima +7 more
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Experimental Brain Research, 1991
In view of the role of serotonin in adrenocortical regulation, the effects of depletion of hypothalamic serotonin, using localized injections of the neurotoxin 5,7-dihydroxytryptamine into the hypothalamic paraventricular nucleus, on the rise in plasma corticosterone following afferent neural stimulation, were studied.
S, Feldman +3 more
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In view of the role of serotonin in adrenocortical regulation, the effects of depletion of hypothalamic serotonin, using localized injections of the neurotoxin 5,7-dihydroxytryptamine into the hypothalamic paraventricular nucleus, on the rise in plasma corticosterone following afferent neural stimulation, were studied.
S, Feldman +3 more
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Annals of the New York Academy of Sciences, 1977
Hypophysectomy leads to a small increase in tyrosine hydroxylase activity of all brain areas containing noradrenergic neurons or tuberoinfundibular dopamine neurons, but nigroneostriatal dopamine neurons are not so affected. ACTH or corticosterone treatment inhibited this effect of hypophysectomy in some noradrenergic neurons and in tuberoinfundibular ...
G R, Van Loon +4 more
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Hypophysectomy leads to a small increase in tyrosine hydroxylase activity of all brain areas containing noradrenergic neurons or tuberoinfundibular dopamine neurons, but nigroneostriatal dopamine neurons are not so affected. ACTH or corticosterone treatment inhibited this effect of hypophysectomy in some noradrenergic neurons and in tuberoinfundibular ...
G R, Van Loon +4 more
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American Journal of Hypertension, 1990
Studies were made on whether oral or intraventricular (icv) NaCl had different effects on the blood pressure (BP) of Dahl rats. Five groups of each strain of Dahl rats, salt-sensitive (S) and salt-resistant (R) rats, were given, respectively, a diet containing 0.3% and icv infusion of 0.15 mol/L NaCl (group 1, control group) or 0.8 mol/L NaCl (group 2),
K, Katahira +5 more
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Studies were made on whether oral or intraventricular (icv) NaCl had different effects on the blood pressure (BP) of Dahl rats. Five groups of each strain of Dahl rats, salt-sensitive (S) and salt-resistant (R) rats, were given, respectively, a diet containing 0.3% and icv infusion of 0.15 mol/L NaCl (group 1, control group) or 0.8 mol/L NaCl (group 2),
K, Katahira +5 more
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Neuropharmacology, 1987
Chronic administration of desipramine resulted in a significant decrease in the degree of stimulation of production of cyclic AMP by noradrenaline, isoproterenol and forskolin in slices of the cerebral cortex of the rat. In preparations of membranes from similarly treated animals, GppNHp- and forskolin-stimulated adenylate cyclase activity was ...
M E, Newman, M, Lipot, B, Lerer
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Chronic administration of desipramine resulted in a significant decrease in the degree of stimulation of production of cyclic AMP by noradrenaline, isoproterenol and forskolin in slices of the cerebral cortex of the rat. In preparations of membranes from similarly treated animals, GppNHp- and forskolin-stimulated adenylate cyclase activity was ...
M E, Newman, M, Lipot, B, Lerer
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Journal of the Autonomic Nervous System, 1991
Corticotropin-releasing factor (CRF) modifies cardiovascular function and hemodynamic status after administration into the central nervous system and into the peripheral circulation. The mechanisms by which CRF alters arterial pressure and heart rate have been examined in detail whereas little information exists regarding the processes mediating CRF ...
J M, Overton, L A, Fisher
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Corticotropin-releasing factor (CRF) modifies cardiovascular function and hemodynamic status after administration into the central nervous system and into the peripheral circulation. The mechanisms by which CRF alters arterial pressure and heart rate have been examined in detail whereas little information exists regarding the processes mediating CRF ...
J M, Overton, L A, Fisher
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Alcohol, 1987
In an earlier study ethanol drinking was induced by reducing mice to 80% of their free-feeding weight and feeding them their daily food allotment prior to the experimental session. The mice were given an ascending series of ethanol concentrations (1 to 8%).
G I, Elmer, R A, Meisch, F R, George
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In an earlier study ethanol drinking was induced by reducing mice to 80% of their free-feeding weight and feeding them their daily food allotment prior to the experimental session. The mice were given an ascending series of ethanol concentrations (1 to 8%).
G I, Elmer, R A, Meisch, F R, George
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