Results 21 to 30 of about 9,592 (218)
Diffuse intrinsic pontine glioma: current insights and future directions
Chinese Neurosurgical Journal, 2021 Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain tumor and the leading cause of brain tumor–related death in children. As several clinical trials over the past few decades have led to no significant improvements in outcome, the current
Dilakshan Srikanthan +5 more
doaj +1 more source
Diffuse intrinsic pontine glioma biopsy: A single institution experience [PDF]
, 2014 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109626/1/pbc25224 ...
Altinok, Deniz +6 more
core +1 more source
H3 K27M-Altered Diffuse Midline Gliomas: A Review
Indian Journal of Neurosurgery, 2023 Diffuse midline glioma H3 K27M-altered is a recently renamed high-grade glioma in the 2021 World Health Organization (WHO) Classification of Central Nervous System Tumors, previously being labelled diffuse midline glioma H3 K27M-mutant in the 2016 update
Karol Wiśniewski +3 more
doaj +1 more source
Survival rates and prognostic predictors of high grade brain stem gliomas in childhood : a systematic review and meta-analysis [PDF]
, 2017 Diagnosis of a pediatric high grade brain stem glioma is devastating with dismal outcomes. This systematic review and meta-analysis was undertaken to determine the survival rates and assess potential prognostic factors including selected interventions ...
Hassan, Hadeel +3 more
core +1 more source
Folia Neuropathologica, 2021 Diffuse midline gliomas, H3 K27M-mutant, World Health Organization (WHO) grade IV represent a distinct glioma entity with a predominantly paediatric presentation and remarkably poor prognosis.
Kristof Babarczy +8 more
doaj +1 more source
Nature Communications, 2019 The oncolytic virus Delta-24-RGD is in clinical trial for adult glioma. Here, the authors show that this virus elicits an immune response in mouse models of pediatric high-grade glioma and diffuse pontine intrinsic glioma, resulting in improved survival.
Naiara Martínez-Vélez +29 more
doaj +1 more source
Diffuse midline glioma with H3 K27M-mutation in an 83-year-old woman
CNS Oncology, 2021 Diffuse midline gliomas harboring histone H3 K27M mutations are most commonly found in the brainstem of children. This mutation confers a WHO grade IV designation and is associated with a particularly poor prognosis.
Justin Thomas Low +2 more
doaj +1 more source
State of affairs in use of steroids in diffuse intrinsic pontine glioma: an international survey and a review of the literature [PDF]
, 2016 Children diagnosed with diffuse intrinsic pontine glioma (DIPG) face a dismal prognosis, with severe neurologic deterioration and inevitable death at a median of 9 months from diagnosis.
Cruz, O +4 more
core +1 more source
An efficient method for the transduction of primary pediatric glioma neurospheres
MethodsX, 2018 Pediatric high grade glioma (pHGG) and diffuse intrinsic pontine glioma (DIPG) are rare, but rapidly fatal malignancies of the central nervous system (CNS), and the leading cause of cancer-related death in children.
Michaël H. Meel +4 more
doaj +1 more source
Diffuse midline glioma-H3K27M mutant. A novel entity with a defining and specific IHC marker
Indian Journal of Pathology and Microbiology, 2021 Diffuse Midline Glioma-H3K27M mutant is a specific entity added to the 2016 updated WHO classification of CNS tumours that represents the majority of diffuse intrinsic pontine gliomas, although identical tumours are also found elsewhere in the midline ...
Prachi Agarwal, Hema Malini Aiyer
doaj +1 more source