Results 111 to 120 of about 6,667 (221)

DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) [PDF]

open access: yesNeuro-Oncology, 2012
M. Zaghloul   +195 more
openaire   +1 more source

Pre-Clinical Models of Diffuse Intrinsic Pontine Glioma

open access: yesFrontiers in Oncology, 2015
Diffuse Intrinsic Pontine Glioma (DIPG) is a rare and incurable brain tumor that arises in the brainstem of children predominantly between the ages of six and eight.
Oren J Becher   +3 more
doaj   +1 more source

Diffuse Intrinsic Pontine Glioma [PDF]

open access: yes, 2018
Diffuse intrinsic pontine glioma (DIPG) is a leading cause of brain cancer-related death in children. These aggressive high-grade gliomas cannot be effectively treated and are associated with dismal prognosis.
Gottardo, Nicholas G., Valvi, Santosh
core   +2 more sources

An oncohistone-driven H3.3K27M/CREB5/ID1 axis maintains the stemness and malignancy of diffuse intrinsic pontine glioma

open access: yesNature Communications
Diffuse intrinsic pontine glioma (DIPG), a lethal pediatric cancer driven by H3K27M oncohistones, exhibits aberrant epigenetic regulation and stem-like cell states.
Wei Zhou   +12 more
doaj   +1 more source

Tumor volume features predict survival outcomes for patients diagnosed with diffuse intrinsic pontine glioma [PDF]

open access: yes
BACKGROUND Diffuse intrinsic pontine glioma (DIPG) is a fatal childhood central nervous system tumor. Diagnosis and monitoring of tumor response to therapy is based on magnetic resonance imaging (MRI).
Bonner, Erin R   +11 more
core   +1 more source

Predicting outcome in childhood diffuse midline gliomas using magnetic resonance imaging based texture analysis [PDF]

open access: yes, 2021
BACKGROUND: Diffuse midline gliomas (DMG) are aggressive brain tumours, previously known as diffuse intrinsic pontine gliomas (DIPG), with 10% overall survival (OS) at 18 months.
Endozo, R   +7 more
core  

DIPG-13. TRANSCRIPTIONAL DEPENDENCIES IN DIFFUSE INTRINSIC PONTINE GLIOMA [PDF]

open access: yesNeuro-Oncology, 2017
Surya Nagaraja   +15 more
openaire   +1 more source

Transcriptomic and epigenetic profiling of ‘diffuse midline gliomas, H3 K27M-mutant’ discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location

open access: yesActa Neuropathologica Communications, 2018
Diffuse midline glioma (DMG), H3 K27M-mutant, is a new entity in the updated WHO classification grouping together diffuse intrinsic pontine gliomas and infiltrating glial neoplasms of the midline harboring the same canonical mutation at the Lysine 27 of ...
David Castel   +14 more
doaj   +1 more source

H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers

open access: yeseLife, 2018
Expression of histone H3.3K27M mutant proteins in human diffuse intrinsic pontine glioma (DIPG) results in a global reduction of tri-methylation of H3K27 (H3K27me3), and paradoxically, H3K27me3 peaks remain at hundreds of genomic loci, a dichotomous ...
Dong Fang   +7 more
doaj   +1 more source

Diffuse intrinsic pontine glioma (DIPG): A qualitative study [PDF]

open access: yes, 2017
Diffuse Intrinsic Pontine Glioma (DIPG); A Qualitative Study: The purpose of this study is to better understand potential warning signs of DIPG in early child development, bring public awareness of this lethal cancer, and support for ongoing research to ...
Deaner, Amy Elizabeth
core   +1 more source

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