Results 1 to 10 of about 2,658,324 (264)

Modeling brain and neural crest neoplasms with human pluripotent stem cells.

Neuro-Oncology, 2023
Abstract Pluripotent stem cells offer unique avenues to study human-specific aspects of disease and are a highly versatile tool in cancer research. Oncogenic processes and developmental programs often share overlapping transcriptomic and epigenetic signatures, which can be reactivated in induced pluripotent stem cells. With the emergence
Lena M Kutscher, Cedar Schloo
exaly   +3 more sources

Myelodysplasia From Valproic Acid Resolved by Cessation [PDF]

Case Reports in Hematology
Myelodysplastic neoplasms (MDS) are clonal blood disorders that cause ineffective hematopoiesis, low blood counts, and a risk of progression to acute myeloid leukemia. Chemotherapy and radiation usually drive these changes, but a small set of medications,
Chidiebube Ugwu, Angimar Uriepero Palma, Rekha Bhat, Alankrita Taneja   +3 more
doaj   +2 more sources

Cesarean section in spinal anesthesia on a patient with mesencephalic tumor and ventriculoperitoneal drainage -A case report- [PDF]

Korean Journal of Anesthesiology, 2012
A seventeen-year-old pregnant woman with a mesencephalic tumor and ventriculoperitoneal (VP) drainage was admitted to the hospital at full term pregnancy to give birth.
Ivana Hirs, Patricia Grbcic
doaj   +1 more source

Is There Such a Thing as a Genuine Cancer Stem Cell Marker? Perspectives from the Gut, the Brain and the Dental Pulp

Biology, 2020
The conversion of healthy stem cells into cancer stem cells (CSCs) is believed to underlie tumor relapse after surgical removal and fuel tumor growth and invasiveness. CSCs often arise from the malignant transformation of resident multipotent stem cells,
Crende Olatz, García-Gallastegui Patricia, Luzuriaga Jon, Badiola Iker, de la Hoz Carmen, Unda Fernando, Ibarretxe Gaskon, Pineda Jose Ramon   +7 more
doaj   +1 more source

Human BCAS3 expression in embryonic stem cells and vascular precursors suggests a role in human embryogenesis and tumor angiogenesis. [PDF]

PLoS ONE, 2007
Cancer is often associated with multiple and progressive genetic alterations in genes that are important for normal development. BCAS3 (Breast Cancer Amplified Sequence 3) is a gene of unknown function on human chromosome 17q23, a region associated with ...
Kavitha Siva, Parvathy Venu, Anita Mahadevan, Shankar S K, Maneesha S Inamdar   +4 more
doaj   +1 more source

The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway

Cell Death and Disease, 2023
Glioma is the most aggressive and common malignant neoplasms in human brain tumors. Numerous studies have showed that glioma stem cells (GSCs)drive the malignant progression of gliomas. Recent studies have revealed that circRNAs can maintain stemness and
Hao Li, Yang Jiang, Jinpeng Hu, Jinkun Xu, Lian Chen, Guoqing Zhang, Junshuang Zhao, Shengliang Zong, Zhengting Guo, Xinqiao Li, Xiang Zhao, Zhitao Jing   +11 more
doaj   +1 more source

Brainstem tumor as a cause of headache triggered by Valsalva maneuver

Headache Medicine, 2021
Expansive lesions of the posterior fossa or the malformation in the occipitocervical transition can cause headache triggered by Valsalva maneuver, usually of sudden onset and of significant intensity, which usually lasts for a short time.
Marcelo Moraes Valença, Martina Falcão Valença, Juliana Ramos Andrade, Elayne Cristina de Oliveira Ribeiro, Luiz Severo Bem Junior, Ana Cristina Veiga Silva, Rita de Cássia Ferreira Valença Mota, Ubiratan Alves Viturino da Silva , José Ronaldo Lessa Angelo Júnior   +8 more
doaj   +1 more source

Neurocognitive Dysfunction in Brain Tumor Patients following Radiation Therapy: A Review of Biological Hypotheses, Current Treatment Outcomes, and Novel Therapeutic Strategies

Marshall Journal of Medicine, 2016
Given the difficulty of surgical resection of brain neoplasms located adjacent to vital structures of the brain as well as the challenges posed by the blood-brain-barrier for the efficacy of chemotherapeutic agents, whole brain radiation therapy (WBRT ...
Raj Singh
doaj   +1 more source

CONTENT OF STEM TUMOR CD133+ CELLS IN BRAIN NEOPLASMS OF DIFFERENT HISTOLOGICAL TYPE [PDF]

Experimental Oncology, 2017
Today, there are conflicting data on the content of cancer stem cells responsible for recurrence and resistance to chemotherapy in tumors of human brain. The aim of the study was to analyze the content of CD133+ cells in different brain tumors by immunofluorescence assay and immunohistochemical method.
Lisyaniy, N.I., Stanetskaya, D.N., Lisyaniy, A.N., Belskaya, L.N.   +3 more
openaire   +3 more sources

Diffuse Midline Gliomas Harboring the H3 K27M-Mutation in the Bilateral Thalamus and Midbrain: A Case Report and a Review of the Literature

대한영상의학회지, 2017
The diffuse midline glioma H3 K27M-mutant was only added recently to the World Health Organization (WHO) Classification of Tumours of the Central Nervous System.
In Kyeom Kim, Jin Woo Kim, Yoon Joon Hwang, Byung Hoon Lee, Jung Wook Seo   +4 more
doaj   +1 more source