Epigenetic Activation of SOX11 in Lymphoid Neoplasms by Histone Modifications [PDF]
, 2011 Recent studies have shown aberrant expression of SOX11 in various types of aggressive B-cell neoplasms. To elucidate the molecular mechanisms leading to such deregulation, we performed a comprehensive SOX11 gene expression and epigenetic study in stem ...
Amador Virginia +107 more
core +1 more source
Neural stem cells in Drosophila : molecular genetic mechanisms underlying normal neural proliferation and abnormal brain tumor formation [PDF]
, 2012 Neural stem cells in Drosophila are currently one of the best model systems for understanding stem cell biology during normal development and during abnormal development of stem cell-derived brain tumors.
Heinrich Reichert +3 more
core +1 more source
Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural Stem cell specification into oligodendrocytes and glutamatergic neurons [PDF]
, 2014 In the postnatal and adult central nervous system (CNS), the subventricular zone (SVZ) of the forebrain is the main source of neural stem cells (NSCs) that generate olfactory neurons and oligodendrocytes (OLs), the myelinating cells of the CNS.
Raineteau, Olivier +17 more
core +1 more source
Drosophila Neural Stem Cells in Brain Development and Tumor Formation [PDF]
, 2014 Neuroblasts, the neural stem cells in Drosophila, generate the complex neural structure of the central nervous system. Significant progress has been made in understanding the mechanisms regulating the self-renewal, proliferation, and differentiation in ...
Reichert, Heinrich, Jiang, Yanrui
core +1 more source
Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting [PDF]
, 2012 INTRODUCTION: Transplantation of neural stem cells (NSCs) is increasingly suggested to become part of future therapeutic approaches to improve functional outcome of various central nervous system disorders. However, recently it has become clear that only
Van Der Linden, Anne-Marie +24 more
core +1 more source
Heliyon, 2021 Hydatid disease (HD), also known as echinococcal disease or echinococcosis, is a worldwide zoonosis with a wide geographic distribution. It can be found in almost all parts of the body and usually remains silent for a long period of time.
Bita Abbasi +8 more
doaj +1 more source
Isolated Post-Traumatic Syringobulbia; Case Report and Review of the Literature [PDF]
Bulletin of Emergency and Trauma, 2014 Syringobulbiais very rare condition defined as slit-like fluid cavity in the brain stem. Several conditions have been reported to be associated with syringobulbia including neoplasms, spinal cord traumas or lesions such as tethered cord, hind-brain ...
Mousa Taghipour +2 more
doaj +2 more sources
Cancer Biology & Medicine, 2021 Objective: Glioma is a highly invasive tumor, frequently disposed in essential areas of the brain, which makes its surgical excision extremely difficult; meanwhile adjuvant therapy remains quite ineffective.
Evgeniya V. Dolgova +21 more
doaj +1 more source
Skp2 modulates proliferation, senescence and tumorigenesis of glioma
Cancer Cell International, 2020 Background Gliomas represent the largest class of primary central nervous system neoplasms, many subtypes of which exhibit poor prognoses. Surgery followed by radiotherapy and chemotherapy has been used as a standard strategy but yielded unsatisfactory ...
Juan Wu +16 more
doaj +1 more source
Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. [PDF]
, 2005 Pluripotent mouse embryonic stem (ES) cells multiply in simple monoculture by symmetrical divisions. In vivo, however, stem cells are generally thought to depend on specialised cellular microenvironments and to undergo predominantly asymmetric divisions.
Luciano Conti +68 more
core +1 more source