Neural stem cells, which are capable of multi-potential differentiation and self-renewal, have recently been shown to have clinical potential for repairing central nervous system tissue damage. However, the theme trends and knowledge structures for human
Wen-Juan Wei +5 more
doaj +1 more source
Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/β-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids. [PDF]
Medulloblastoma (MB), a neuroectodermal tumor arising in the cerebellum, represents the most frequent childhood brain malignancy. Current treatments for MB combine radiation and chemotherapy and are often associated with relevant side effects; novel ...
Barbara Bassani +7 more
doaj +1 more source
Tectal glioblastoma Glioblastoma tetal
Brain stem gliomas are a heterogeneous group of neoplasms arising mostly in paediatric patients. Tectal plate gliomas represent a particular type of brain stem tumours usually with a benign, indolent clinical course, presenting with signs of raised ...
Feres Chaddad Neto +5 more
doaj +1 more source
Torticollis as a Rare Presentation of Cerebellopontine Angle Choroid Plexus Papilloma in Children [PDF]
Background and Importance: The rare intracranial neoplasms are Choroid Plexus Papillomas (CPPs), especially in the cerebellopontine angle. The main location of choroid plexus papillomas in adults and children are 4th ventricle and lateral ventricles ...
Mohammad Faraji-Rad +2 more
doaj
Pediatric Non–Brain Stem High-Grade Glioma: A Single-Center Experience
Background Pediatric high-grade gliomas (PHGGs) consist of a heterogeneous class of central nervous system (CNS) neoplasms with a poor prognosis. We aimed to present our 10-year experience in the management of children with high-grade glioma focusing on ...
Ehsan Alimohammadi +4 more
doaj +1 more source
Benefit-risk profile of cytoreductive drugs along with antiplatelet and antithrombotic therapy after transient ischemic attack or ischemic stroke in myeloproliferative neoplasms [PDF]
We analyzed 597 patients with myeloproliferative neoplasms (MPN) who presented transient ischemic attacks (TIA, n = 270) or ischemic stroke (IS, n = 327). Treatment included aspirin, oral anticoagulants, and cytoreductive drugs.
Arellano-Rodrigo, Eduardo +41 more
core +5 more sources
The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]
Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J +3 more
core
Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited [PDF]
The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-angiogenic cancer therapy are major issues in almost all current concepts of both cancer biology and targeted cancer therapy. Currently, (1) sprouting angiogenesis, (2)
Dumont, Daniel J. +2 more
core +1 more source
The Evolving Role of CD8+CD28- Immunosenescent T Cells in Cancer Immunology [PDF]
Functional, tumor-specific CD8+ cytotoxic T lymphocytes drive the adaptive immune response to cancer. Thus, induction of their activity is the ultimate aim of all immunotherapies.
Dey, Mahua +4 more
core +1 more source
Objective Preliminary study on the protective effect of intraoperative direct electrical stimulation motor ⁃ evoked potential (DES ⁃ MEP) on motor function during brainstem tumor surgery.
Xiao⁃rong TAO +6 more
doaj

