Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
ABC of Brain Stem Death: From Brain Death to Brain Stem Death
, 1982 In the second in a series of nine articles on brain death, a British neurologist traces the evolution of British and American criteria for establishing brain death, distinguishes between whole brain death and death of the brain stem, and describes the ...
Pallis, Christopher
core +1 more source
Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells [PDF]
, 2006 Embryonic cortical neural stem cells apparently have a transient existence, as they do not persist in the adult cortex. We sought to determine the fate of embryonic cortical stem cells by following Emx1(IREScre); LacZ/EGFP double-transgenic murine cells ...
Seaberg, R.M. +18 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Comparative Analysis of the Frequency and Distribution of Stem and Progenitor Cells in the Adult Mouse Brain [PDF]
cells (NSCs) and progenitor cells, but it cannot discriminate between these two populations. Given two assays have purported to overcome this shortfall, we performed a comparative analysis of the distribution and frequency of NSCs and progenitor ...
Golmohammadi, Mohammed G. +17 more
core +1 more source
Conditional activation of Bmi1 in embryonic and postnatal neural stem/progenitor cells in mouse models: analysis of its effect on their biological properties and tumourigenesis [PDF]
, 2011 PhDThe Polycomb group protein Bmi1 is a key transcriptional regulator of self renewal of embryonic and adult neural stem and progenitor cells (NSPC) and its over-expression has been shown to occur in several types of brain tumour.
Yadırgı, Gökhan
core +4 more sources
PAPILLARY GLIONEURONAL TUMOR OF THE POSTERIOR FOSSA
Revista Ciencias Biomédicas, 2015 Introduction: the papillary glioneuronal tumor (PGT) is an uncommon disease and it has recent categorization. It has probable origin in the pluripotent stem cells of the subependymal zone that is located mainly around the temporal horns of the lateral
Tuñón-Pitalúa Martha Cecilia +5 more
doaj
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
"Does gender matter when teaching STEM?" : Australian primary teachers speak
, 2021 Current literature illuminates that primary school teachers lack the skills and confidence required to teach STEM subjects effectively. This a recurring theme in the literature and a cause for concern.
Skillen, Maree A. (R17785) +2 more
core
FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal [PDF]
, 2012 Drosophila neuroblasts (NBs) have emerged as a model for stem cell biology that is ideal for genetic analysis but is limited by the lack of cell-type-specific gene expression data.
Jonas Steinmann +17 more
core +1 more source