Results 121 to 130 of about 6,667 (221)

Diffuse intrinsic pontine glioma: DIPG [PDF]

, 2022
openaire   +1 more source

Rapid Peroxide Removal Limits the Radiosensitization of Diffuse Intrinsic Pontine Glioma (DIPG) Cells by Pharmacologic Ascorbate. [PDF]

Radiat Res, 2023
Solst SR, Mapuskar KA, Graham CH, King SA, Rheem R, Current K, Allen BG, Caster JM, Spitz DR, Howard ME.   +9 more
europepmc   +1 more source

Laminin-associated integrins mediate Diffuse Intrinsic Pontine Glioma infiltration and therapy response within a neural assembloid model

Acta Neuropathologica Communications
Diffuse Intrinsic Pontine Glioma (DIPG) is a highly aggressive and fatal pediatric brain cancer. One pre-requisite for tumor cells to infiltrate is adhesion to extracellular matrix (ECM) components.
Sauradeep Sinha, Michelle S. Huang, Georgios Mikos, Yudhishtar Bedi, Luis Soto, Sarah Lensch, Manish Ayushman, Lacramioara Bintu, Nidhi Bhutani, Sarah C. Heilshorn, Fan Yang   +10 more
doaj   +1 more source

DIPG-28. NTRK FUSIONS IN PEDIATRIC DIFFUSE INTRINSIC PONTINE GLIOMAS [PDF]

Neuro-Oncology, 2019
Nathan Dahl, Andrew Donson, Dong Wang, Nicholas Foreman, Suzanne Baker, Christopher Tinkle, Chris Jones, Simon Bailey, Rajeev Vibhakar, Lindsey Hoffman   +9 more
openaire   +1 more source

PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma

The Journal of Clinical Investigation
Diffuse midline glioma (DMG), including tumors diagnosed in the brainstem (diffuse intrinsic pontine glioma; DIPG), are uniformly fatal brain tumors that lack effective treatment.
Ryan J. Duchatel, Evangeline R. Jackson, Sarah G. Parackal, Dylan Kiltschewskij, Izac J. Findlay, Abdul Mannan, Dilana E. Staudt, Bryce C. Thomas, Zacary P. Germon, Sandra Laternser, Padraic S. Kearney, M. Fairuz B. Jamaluddin, Alicia M. Douglas, Tyrone Beitaki, Holly P. McEwen, Mika L. Persson, Emily A. Hocke, Vaibhav Jain, Michael Aksu, Elizabeth E. Manning, Heather C. Murray, Nicole M. Verrills, Claire Xin Sun, Paul Daniel, Ricardo E. Vilain, David A. Skerrett-Byrne, Brett Nixon, Susan Hua, Charles E. de Bock, Yolanda Colino-Sanguino, Fatima Valdes-Mora, Maria Tsoli, David S. Ziegler, Murray J. Cairns, Eric H. Raabe, Nicholas A. Vitanza, Esther Hulleman, Timothy N. Phoenix, Carl Koschmann, Frank Alvaro, Christopher V. Dayas, Christopher L. Tinkle, Helen Wheeler, James R. Whittle, David D. Eisenstat, Ron Firestein, Sabine Mueller, Santosh Valvi, Jordan R. Hansford, David M. Ashley, Simon G. Gregory, Lindsay B. Kilburn, Javad Nazarian, Jason E. Cain, Matthew D. Dun   +54 more
doaj   +1 more source

DIPG-47. RE-IRRADIATION FOR RECURRENT DIFFUSE INTRINSIC PONTINE GLIOMA [PDF]

Neuro-Oncology, 2018
Yui Kimura, Keita Terashima, Chikako Kiyotani, Tomoo Osumi, Yoko Shioda, Motohiro Kato, Daisuke Tomizawa, Hiroshi Fuji, Kenichi Usami, Hidekazu Aoki, Rie Irie, Hideki Ogiwara, Yoshiyuki Tsutsumi, Takako Yoshioka, Kimikazu Matsumoto   +14 more
openaire   +1 more source

The Role of Reirradiation in Childhood Progressive Diffuse Intrinsic Pontine Glioma (DIPG): An Ongoing Challenge beyond Radiobiology. [PDF]

Brain Sci, 2023
Lo Greco MC, Milazzotto R, Liardo RLE, Foti PV, Palmucci S, Basile A, Pergolizzi S, Spatola C.   +7 more
europepmc   +1 more source

Spatial analysis of a complete DIPG-infiltrated brainstem reveals novel ligand-receptor mediators of tumour-to-TME crosstalk

Acta Neuropathologica Communications
Previous studies have highlighted the capacity of brain cancer cells to functionally interact with the tumour microenvironment (TME). This TME-cancer crosstalk crucially contributes to tumour cell invasion and disease progression.
Anja Kordowski, Onkar Mulay, Xiao Tan, Tuan Vo, Ulrich Baumgartner, Mellissa K. Maybury, Timothy Hassall, Lachlan Harris, Quan Nguyen, Bryan W. Day   +9 more
doaj   +1 more source

Pediatric high-grade glioma: biologically and clinically in need of new thinking. [PDF]

, 2017
High-grade gliomas in children are different from those that arise in adults. Recent collaborative molecular analyses of these rare cancers have revealed previously unappreciated connections among chromatin regulation, developmental signaling, and ...
+several additional authors, Baker, Suzanne J, Jones, Chris, Jones, David T W, Karajannis, Matthias A, Kieran, Mark W, Monje, Michelle, Packer, Roger J   +7 more
core   +1 more source

Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma

Nature Communications
Diffuse intrinsic pontine glioma (DIPG) is a fatal brainstem tumor desperately in need of better treatments. Chimeric antigen receptor (CAR) T cell therapies for DIPG have demonstrated clinical tolerability and bioactivity, but not universal benefit.
Edward Z. Song, Andrea Timpanaro, Michael Meechan, Leonel Elena-Sanchez, Lucy Z. Li, Sophie Jamet, Davina S. Lau, Lily I. Winter, Matthew D. Dun, Jessica B. Foster, Myron K. Evans, Siobhan S. Pattwell, Vandana Kalia, Surojit Sarkar, Michael C. Jensen, Matthew C. Biery, Nicholas A. Vitanza   +16 more
doaj   +1 more source