Results 111 to 120 of about 3,615,865 (367)

Implementing the Three-Equation Method of Measuring Single Breath Carbon Monoxide Diffusing Capacity

open access: yesCanadian Respiratory Journal, 1996
Conventional methods of measuring the single breath diffusing capacity of the lung for carbon monoxide (DLcoSB) are based on the Krogh equation, which is valid only during breath holding.
Brian L Graham   +2 more
doaj   +1 more source

Capacity allocation through neural network layers [PDF]

open access: yesarXiv, 2019
Capacity analysis has been recently introduced as a way to analyze how linear models distribute their modelling capacity across the input space. In this paper, we extend the notion of capacity allocation to the case of neural networks with non-linear layers.
arxiv  

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Quantitative morphology of compensatory lung growth

open access: yesEuropean Respiratory Review, 2006
Compensatory lung growth is defined by the absolute increases in the quantity of functioning lung tissue in response to injury and/or disease, leading to a positive impact on functional outcome. The pneumonectomy model is used as an example to illustrate
C. C. W. Hsia
doaj  

Acute effects of combined exercise and oscillatory positive expiratory pressure therapy on sputum properties and lung diffusing capacity in cystic fibrosis: a randomized, controlled, crossover trial

open access: yesBMC Pulmonary Medicine, 2018
Background Regular airway clearance by chest physiotherapy and/or exercise is critical to lung health in cystic fibrosis (CF). Combination of cycling exercise and chest physiotherapy using the Flutter® device on sputum properties has not yet been ...
Thomas Radtke   +7 more
doaj   +1 more source

Uniqueness of diffusion operators and capacity estimates [PDF]

open access: yesJournal of Evolution Equations, 2013
Let $ $ be a connected open subset of $\Ri^d$. We analyze $L_1$-uniqueness of real second-order partial differential operators $H=-\sum^d_{k,l=1}\partial_k\,c_{kl}\,\partial_l$ and $K=H+\sum^d_{k=1}c_k\,\partial_k+c_0$ on $ $ where $c_{kl}=c_{lk}\in W^{1,\infty}_{\rm loc}( ), c_k\in L_{\infty,{\rm loc}}( )$, $c_0\in L_{2,{\rm loc}}( )$ and $C(x)=(
openaire   +4 more sources

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Skin thickness score as a surrogate marker of organ involvements in systemic sclerosis: a retrospective observational study

open access: yesArthritis Research & Therapy, 2019
Background Previous studies have shown the relationship between higher skin thickness score and the existence of organ involvements in systemic sclerosis (SSc).
Kazuki M. Matsuda   +11 more
doaj   +1 more source

Convergence of symmetric diffusions on Wiener spaces [PDF]

open access: yesActa Math. Appl. Sin. Vol. 20, No.1 (2004), 19-24, 2003
We prove convergence of symmetric diffusions on Wiener spaces by using stopping times arguments and capacity techniques. The drifts of the diffusions can be singular, we require the densities of the processes to be neither bounded from above nor away from zero.
arxiv  

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