Results 111 to 120 of about 3,778,907 (367)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Lung Volumes and Diffusing Capacity in Bronchiectasis : Correlation with the Findings of High Resolutional CT [PDF]

, 1999
Yeon Jae Kim, Jae Yong Park, Jun Hee Won, Chang Ho Kim, Duk Sik Kang, Tae Hoon Jung   +5 more
openalex   +1 more source

Implementing the Three-Equation Method of Measuring Single Breath Carbon Monoxide Diffusing Capacity

Canadian Respiratory Journal, 1996
Conventional methods of measuring the single breath diffusing capacity of the lung for carbon monoxide (DLcoSB) are based on the Krogh equation, which is valid only during breath holding.
Brian L Graham, Joseph T Mink, David J Cotton   +2 more
doaj   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

A functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacity [PDF]

, 2018
Chenchen Zhang, Clare D. Ramsey, Andrew Berical, Liu Yi Yu, Lin Leng, Kathleen A. McGinnis, Yan Song, H. Michael, Meredith C. McCormack, Heather Allore, Alison Morris, Kristina Crothers, Richard Bucala, Chun Geun Lee, Maor Sauler   +14 more
openalex   +1 more source

Mexican Hispanics show significant improvement in lung function approximately 1 year after having severe COVID‐19

Experimental Physiology
The long‐term effects of COVID‐19 on lung function are not understood, especially for periods extending beyond 1 year after infection. This observational, longitudinal study investigated lung function in Mexican Hispanics who experienced severe COVID‐19,
Arturo Cortes‐Telles, Luis Alberto Solís‐Díaz, Heidegger Mateos‐Toledo, Jordan A. Guenette, Gerald Stanley Zavorsky   +4 more
doaj   +1 more source

Nutritional status and airflow obstruction: two independent contributors to CO diffusing capacity impairment in COPD

Monaldi Archives for Chest Disease, 2005
Background. The association between weight loss and Chronic Obstructive Pulmonary Disease (COPD) has been recognised from many years. Based on the evidence that nutritional status reflects metabolic disturbances in COPD, the relationship between body ...
S. Baldi, G.D. Pinna, P. Crotti, S. Montemartini, E. Dacosto, F. Fanfulla, C. Fracchia, C. Bruschi   +7 more
doaj   +1 more source

Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. [PDF]

, 2019
RNA Polymerase II (Pol II) and transcription factors form concentrated hubs in cells via multivalent protein-protein interactions, often mediated by proteins with intrinsically disordered regions.
Darzacq, Xavier, Dugast-Darzacq, Claire, Hansen, Anders S, Hao, Yvonne, Heckert, Alec Basil, Marie-Nelly, Hervé, McSwiggen, David Trombley, Teves, Sheila S, Tjian, Robert, Umemoto, Kayla K   +9 more
core  

Interpretation of Diffusing Capacity [PDF]

Chest, 2021
openaire   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source